Rats

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The model contains monoallelic deletion of the BDNF gene. Useful in the study of Alzheimer's, depression, pain, nerve growth, loss of memory.
bdnf rat alzheimers 4
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Knockout the gene encoding the ABC transporter, a critical in exporting pump bile salts.
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Knockout model encoding CAR having effects on induction of cytochrome p450s. It has applications in the study of hepatotoxicity, cholestasis and drug metabolism.
Cotton rat
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Model very sensitive to infectious agents of human origin. Ideal for research into the development of vaccines and gene therapy based on adenoviral vectors.
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The model has the deleted gene organic anion transporter 3 OAT3. Useful in clinical drug-drug interactions, toxicity and liver metabolism.
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Model with deletion of DJ-1 gene plays role in protecting neurons from oxidative stress and cell death. Ideal for Parkinson diseases and dopaminergic cell loss research.
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Knockout model to study the role of nuclear receptors in the impact of carcinogenic substances, the compounds of xenobiotic metabolism and hepatotoxicity.
Trpv1 knockout rat
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The model has biallelic TRPV1 gene deletion, which is useful in the study of pain, nociception, analgesia, and thermoregulation.
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Model with expresion of Cre recombinase. For applications in optogenetic, expression and nockout recombined genes and DREADD.
Wistar Wu rat
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General multipurpose model for toxicology and aging studies.
Szczury rozwijające cukrzycę typu 2.
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Nomenklatura: ZDF-Leprfa/Crl Hodowla: krewniacza Pochodzenie:  Mutacja pojawiła się w niekrewniaczej koloni szczurów Zucker hodowanych w latach 1974-1975 w laborator...