Central Nervous System

Add to request
Manufacturer:
Model for cardiovascular research (atherosclerosis, heart abnormalities, hypercholesterolemiam hypertriglyceridemia, vascular defects).
APP Knockout Rat
Add to request
Manufacturer:
Rat model for Alzheimer's research, dementia and other neurodegenerative diseases.
Add to request
Manufacturer:
The model contains monoallelic deletion of the BDNF gene. Useful in the study of Alzheimer's, depression, pain, nerve growth, loss of memory.
CBA mouse
Add to request
Research applications include brain development, neurochemistry and behavioural studies
Add to request
Manufacturer:
Model exhibits a deletion of the Cntnap2 gene and is useful in of studies autism, cell adhesion, and synaptic plasticity.
Disc1 Knockout Rat
Add to request
Manufacturer:
Model with a deletion in Disc1 gene for use in studies of schizophrenia, bipolar disorder and neuronal growth studies.
Add to request
Manufacturer:
Model with expresion of Cre recombinase. For applications in optogenetic, expression and nockout recombined genes and DREADD.
Add to request
Manufacturer:
Model contains a biallelic disruption of the Faah and is useful in cannabioid, nocicepcin and pain research.
Fmr1 Knockout Rat
Add to request
Manufacturer:
Model exhibits the deletion of the FMR1 gene responsible for fragile X syndrome and autism.
Add to request
Manufacturer:
Double knockout contains deletion Lrrk1 and Lrrk2 genes. Ideal for Prkinson research and neuronal apoptosis.
Lrrk1 Knockout Rat
Add to request
Manufacturer:
Model with deletion of the Lrrk1 gene. Ideal for Parkinson's disease and neuronal apoptosis research.
Add to request
Manufacturer:
Model with deletion of the Lrrk2 gene. Ideal for Parkinson's disease and neuronal apoptosis research.
Add to request
Manufacturer:
Laboratory model used to study the mechanism of autism, Rett syndrome, and cognitive function.
Add to request
Manufacturer:
This model contains a biallelic deletion of the metabotropic glutamate receptor 5 (mGluR5 or Grm5). Ideal for fragile X syndrome and autism research.
Add to request
Manufacturer:
Model to study autism spectrum, schizophrenia and synaptic plasticity. Exhibit a deletion of the gene Nrxn1.
Add to request
Manufacturer:
Model of biallelic deletion of a gene Nlgn3 encoding a protein Neuroligin 3, which is linked with autism and Asperger's Syndrome.
Add to request
Manufacturer:
This model possesses an 11 base pair deletion in exon 2 of the Oprm1 gene and is useful in nociceptin and discrimination among opioid receptor subtypes research.
Add to request
Manufacturer:
Model contains a biallelic deletion of the Ngfr gene, encoding for the p75 neurotrophin receptor (p75NTR). Knockout homozygous are useful in pain, nociception and anelgesia research.
Add to request
Manufacturer:
Model with deletion of DJ-1 gene plays role in protecting neurons from oxidative stress and cell death. Ideal for Parkinson diseases and dopaminergic cell loss research.
Pink1 (Park6) Knockout
Add to request
Manufacturer:
Research model for Parkinson's disease and stress induced neurological disfunctions.
Trpv1 knockout rat
Add to request
Manufacturer:
The model has biallelic TRPV1 gene deletion, which is useful in the study of pain, nociception, analgesia, and thermoregulation.
Add to request
Manufacturer:
Model with expresion of Cre recombinase. For applications in optogenetic, expression and nockout recombined genes and DREADD.