Endocrine, metabolic diseases

11BHSD2 Mouse
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Transgenic model to study cardiac hypertrophy and heart failure.
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Laboratory rabbit model with the lack of expression of ApoE responsible for the metabolism of lipids. Used to test atherogenesis, atherosclerosis, diabetes research.
ApoE rat
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Rat model Alzheimer's disease with ApoE knockout for a wide range of studies of type II diabetes, obesity, atherosclerosis, insulin resistance and hypertension.
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Model for cardiovascular research (atherosclerosis, heart abnormalities, hypercholesterolemiam hypertriglyceridemia, vascular defects).
C57 Mouse Charles River
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General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology.
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Knockout model encoding CAR having effects on induction of cytochrome p450s. It has applications in the study of hepatotoxicity, cholestasis and drug metabolism.
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Model with the lack of expression of the CFTR protein leads to cystic fibrosis and disruption of transport of chloride and thiocyanates.
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Diabetes and obesity research, wound healing.
GLUT 4 Mouse
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Model for a wide range of diabetes studies.
Ldlr rat
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Knockout rats LDLR gene, with a much elevated serum cholesterol. Model for lipoprtein transport and cholesterol studies, type II diabetes, hypertension and atherosclerosis.
Leptin rat
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In vivo model obesity, diabetes, atherosclerosis and hypertension research. Homozygous rats do not express the leptin hormone.
Mouse The Jackson Laboratory C57BL6J
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General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology.
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Knockout model to study the role of nuclear receptors in the impact of carcinogenic substances, the compounds of xenobiotic metabolism and hepatotoxicity.
Szczury rozwijające cukrzycę typu 2.
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Nomenklatura: ZDF-Leprfa/Crl Hodowla: krewniacza Pochodzenie:  Mutacja pojawiła się w niekrewniaczej koloni szczurów Zucker hodowanych w latach 1974-1975 w laborator...