Neurodegenerative diseases

APP Knockout Rat
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Rat model for Alzheimer's research, dementia and other neurodegenerative diseases.
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The model contains monoallelic deletion of the BDNF gene. Useful in the study of Alzheimer's, depression, pain, nerve growth, loss of memory.
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Double knockout contains deletion Lrrk1 and Lrrk2 genes. Ideal for Prkinson research and neuronal apoptosis.
Lrrk1 Knockout Rat
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Model with deletion of the Lrrk1 gene. Ideal for Parkinson's disease and neuronal apoptosis research.
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Model with deletion of the Lrrk2 gene. Ideal for Parkinson's disease and neuronal apoptosis research.
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Model with deletion of DJ-1 gene plays role in protecting neurons from oxidative stress and cell death. Ideal for Parkinson diseases and dopaminergic cell loss research.
Pink1 (Park6) Knockout
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Research model for Parkinson's disease and stress induced neurological disfunctions.