Automated body weight measurement in home cage

Czujnik pomiaru masy ciała TSE Systems

Automated body weight measurement in home cage

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This cost and work-effective module is based on high precision weighing sensor that is mounted to the cage lids for all standard cages commercially available.

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Automated body weight measurement in home cage

A red sit-in tube housing connected to a weighing station enriches the home cage and reports the body weight as the animal visits

Sensor is universal high-precision weighing station that can be mounted to any type of cage lid, e.g. metal wire or Macrolon. Several sensor stations (number depends on the cage type) can be installed per home cage. Body weight tube housing ( or food containers and drinking bottles ) can be flexibly and easily associated to each sensor, which then quantifies the connected weight - with high technical resolution of ~0.01 g, at user-defined time intervals. Sensors with varying measuring ranges are available for rats and mice to assure optimal weighing performance and accuracy.

Key features

  • The universal precision sensors can be flexibly used as body weight stations
  • Fully automated objective quantification of body weight
  • For mice and rats
  • Adjustable height of housing for easy acces by animal
  • Minimal experimenter interference
  • Usable with all standard home cages – no modification required

 

For discrimination experiments (e.g., preference, aversion studies), a variable number of sensor stations can be installed per home cage, e.g. for three diets, water and body weight monitoring (various combinations possible). As integrative part of the PhenoMaster system, the body wiegh module can be combined with any other PhenoMaster module; e.g., feeding & drinking module can be combined, the automated food/liquid access control unit, the operant wall, the indirect gas calorimetry system (CaloSys), and various others.

Al-Ahad Sabbagha NGA, Kao HJ, Yang CF, Huang CC, Lin WD, Tsai F, Chen TH, Tarn WY, Wu JY, Chen YT
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Pediatr Res 2011; 70(1):31-6
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Hollis JH, Jonaidi H, Lemus M, Oldfield BJ
The endocannabinoid Arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression
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Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet
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Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain
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Pfluger PT, Castañeda TR, Heppner KM, Strassburg S, Kruthaupt T, Chaudhary N, Halem H, Culler MD, Datta R, Burget L, Tschöp MH, Nogueiras R, Perez-Tilve D
Ghrelin, peptide YY and their hypothalamic targets differentially regulate spontaneous physical activity
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Rousso-Noori L, Knobler H, Levy-Apter E, Kuperman Y, Neufeld-Cohen A, Keshet Y, Akepati VR, Klinghoffer RA, Chen A, Elson A.
Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner
Cell Metab 2011; 13:562-572
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Rousso-Noori L, Knobler H, Levy-Apter E, Kuperman Y, Neufeld-Cohen A, Keshet Y, Akepati YR, Klinghoffer RA, Chen A, Elson A
Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner
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Glutaminyl cyclase (OC) knok out mice show mild hypothyreodism but absence of hypogonadism: implications for enzyme function and drug development
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Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice
J Clin Invest 2011; 121(6):2413-21
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Steen Petersen P, Jin C, Nygaard Madsen A, Rasmussen M, Kuhre R, Egerod KL, Bo Nielsen L, Schwartz TW, Holst B
Deficiency of the GPR39 receptor os associated with obesity and altered adipocyte metabolism
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Taschler U, Radner FPW, Heier C, Schreiber R, Schweiger M, Schoiswohl G, Preiss-Landl K, Jaeger D, Reiter B, Koefeler HC, Wojciechowski J, Theussl C, Penninger JM, Lass A, Haemmerle G, Rechner R, Zimmermann R
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Distinct effects of calorie restriction and resveratrol on diet-induced obesity and Fatty liver formation
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Verbaeys I, Tolle V, Swennen Q, Zizzari P, Buyse J, Epelbaum J, Cokelaere
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Laforin, a dual specificity phosphatase involved in lafora disease, regulates insulin response and whole-body energy balance in mice
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Microhandling of vesicular glutamate uptake modulate feeding in broilers
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