Elevated plus maze

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Elevated plus maze


The Elevated Plus Maze test is a widely used model for testing anxiety based on the natural aversion of rodents to explore elevated and open spaces. 

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Elevated plus maze

The Elevated Plus Maze test is a widely used model for testing anxiety based on the natural aversion of rodents to explore elevated and open spaces. Four arms are arranged in the shape of a cross – two arms have surrounding walls, the other arms have no walls.

TSE Elevated Plus Mazes can be used in combination with the video tracking system TSE VideoMot2 that offers a dedicated analysis protocol for this paradigm. TSE Elevated Plus Mazes are also available as fully computerized systems with infrared sensors at each arm entrance.

Key features

  • Rat or mouse mazes made of a variety of materials and colors available
  • Removable closed arm walls available for easy cleaning
  • Fully automated system or maze suited for videotracking available
  • Both versions contain easy-to-use Windows software to analyze a variety of basic or sophisticated parameters
  • Measures anxiety, exploration behavior

Geis C, Weishaupt A, Grünewald B, Wultsch T, Reif A, Gerlach M, Dirkx R, Solimena M, Perani D, Heckmann M, Toyka KV, Folli F, Sommer C
Human stiff-person syndrome lgG induces anxious behavior in rats
PLoS ONE 2011; 6(2):
VideoMot, Elevated Plus Maze, RotaRod
Post AM, Weyers P, Holzer P, Painsipp E, Pauli P, Wultsch T, Reif A, Lesch KP
Gene-environment interaction influences anxiety-like behavior in ethologically based mouse models
BBR 2011; 218:99-105
VideoMot, Open Field, Elevated Plus Maze
Asp L, Beraki S, Kristensson K, Ögren SO, Karlsson H
Neonatal infection with neurotropic influenza A virus affects working memory and expression of type III Nrg1 in adult mice
Brain Behav Immun 2009; 23:733-41/
Elevated Plus Maze
Kindlundh-Högberg AMS, Zhang X, Svenningsson P
S100B overexpressing mutant mice exhibit prologned behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA
Int J Neuropsychopharmacol 2008; 12:201-15
Elevated Plus Maze
Elevander-Tottie E, Eriksson TM, Sandin J, Ögren SO
N-methyl-D-aspartate receptors in the medial septal area have a role in spatial and emotional learning in the rat
Neuroscience 2006; 142:963-78
Elevated Plus Maze
Nguyen HP, Kobbe P, Rahne H, Worpel T, Jager B, Stephan M, Pabst R, Holzmann C, Riess O, Korr H, Kantor O, Petrasch-Parwez E, Wetzel R, Osmand A, von Horsten S
Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington’s disease
Hum Mol Genet 2006; 15:3177-94
RotaRod, Elevated Plus Maze, Radial Maze, Active Avoidance
Beraki S, Aronsson F, Karlsson H, Ogren SO, Kristensson K
Influenza A virus infection causes alterations in expression of synaptic regulatory genes combined with changes in cognitive and emotional behaviors in mice
Mol Psych 2005; 10(3):299-308
VideoMot, Elevated Plus Maze
Kuteeva E, Hökfelt T, Ogren SO
Behavioural characterisation of transgenic mice overexpressing galanin under the PDGF-B promoter
Neuropeptides 2005; 39:299-304
VideoMot, Elevated Plus Maze
Kuteeva E, Hökfelt T, Ogren SO
Behavioural characterisation of young adult transgenic mice overexpressing galanin under the PDGF-B promoter
Regul Peptides 2005; 125:67-78
VideoMot, Elevated Plus Maze
Karl T, Hoffmann T, Pabst R, von Hoersten S
Behavioral effects of neuropeptide Y in F344 rat substrains with a reduced dipeptidyl-peptidase IV activity
Pharmacol Biochem Behav 2003; 75:869-79
Elevated Plus Maze
Von Hoersten S et al.
Transgenic rat model of Huntington´s disease
Hum Mol Genet 2003; 12(6):617-24
Elevated Plus Maze, Radial Maze, RotaRod
Breivik T, Stephan M, Brabant GE, Straub RH, Pabst R, von Horsten S.
Postnatal lipopolysaccharide-induced illness predisposes to peridontal disease in adulthood
Brain Behav Immun 2002; 16(4):421-38
Elevated Plus Maze
Schwarzberg H, Kalbacher H, Hoffmann W
Differential behavioral effects of TFF peptides: injections of synthetic TFF3 into the rat amygdala
Pharmacol Biochem Behav 1999; 62(1):173-8
Elevated Plus Maze, InfraMot
videotracking, zvířecí aktivita, aktivita zvíře, video záznam aktivita
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Všestranný videosystém na automatické snímání, zaznamenávání a analyzování aktivity zvířat v multi-komorových prostorech a bludištích.