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Activity & Exploration

Rama badania aktywności wokół CaloCage
Rama wiązek podczerwieni ActiMot
Sensor ruchu MOT pod klatką
TraffiCage do pomiaru zwierząt z wszczepionymi transponderami
VideoMot TSE Systems
VideoMot2 odczyt danych
SE Systems
Różne kołowrotki do systemów TSE

Activity & Exploration

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Rodent exploratory and activity behavior is subject to a variety of external influences such as light, noise, or internal factors like nutrition, handling, diurnal rhythms, and attention status.

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Activity & Exploration

Rodent exploratory and activity behavior is subject to a variety of external influences such as light, noise, or internal factors like nutrition, handling, diurnal rhythms, and attention status, to name just a few. Flexible and variable analyses can be performed with technological solutions by TSE Systems.

Featured products

  • VideoMot2 automatically records animal activity in a multitude of arenas.
  • TSE Systems offers multifunctional 3-dimensional light-beam system for open field units, light-dark tests, and hole board exploration systems.
  • Total activity of one or multiple animals can be measured with InfraMot.
  • The TraffiCage by NewBehavior is an activity monitor for large numbers of transponderized animals.
  • The user-friendly MOT – Motility Meter can be employed with all home cage sizes to detect movements of animals.
  • TSE systems produces a unique range of modular, multifunctional Wolunatry Running Wheels or Forced Running Wheels for varying applications including motivation, anhedonia, operant conditioning, indirect calorimetry or motor skill analysis.
Deblon N, Veyrat-Durebex C, Bourgoin L, Caillon A, Bussier AL, Petrosino S, Piscitelli F, Legros JJ, Geenen V, Foti M, Wahli W, Di Marzo V, Rohner-Jeanrenaud F
Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats
PhenoMaster / LabMaster (Feeding / Drinking, Activity)
Hollis JH, Jonaidi H, Lemus M, Oldfield BJ
The endocannabinoid Arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression
J Neuroimmunol 2011; 233:127-34
PhenoMaster / LabMaster (Calorimetry, Metabolic PhenoCage, Drinking / Feeding, Activity)
Hübener J, Vauti F, Funke C, Wolburg H, Ye Y, Schmidt T, Wolburg-Buchholz K, Schmitt I, Gardyan A, Drießen S, Arnold HH, NguyenHP, Riess O
N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation
Brain 2011; 134:1925-42
PhenoMaster / LabMaster (Drinking / Feeding, Activity), RotaRod
Jamieson PM, Cleasby ME, Kuperman Y, Morton NM, Kelly PAT, Brownstein DG, Mustard KJ, Vaughan JM, Carter RN, Hahn CN, Hardie DG, Seckl JR, Chen A, Vale WW
Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet
Diabetologia 2011; 54:2392-403
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Lin HV, Ren H, Samuel VT, Lee HY, Lu TY, Shulman GI, Accili D
Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues
Diabetes 2011; 60, 3:700-708
PhenoMaster / LabMaster (Calorimetry, Feeding, Activity)
Pfluger PT, Castaneda TR, Heppner KM, Strassburg S, Kruthaupt T, Chaudhary N, Halem H, Culler MD, Datta R, Burget L, Tschöp MH, Nogueiras R, Perez-Tilve D
Ghrelin, peptide YY and their hypothalamic targets differentially regulate spontaneous physical activity
Physiol Behav 2011; 105:52-61
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Ravussin Y, Gutman R, Diano S, Shanabrough M, Borok E, Sarman B, Lehmann A, LeDuc CA, Rosenbaum M, Horvarth TL, Leibel RL
Effects of chronic weight perturbation on energy homeostasis and brain structure in mice
Am J Physiol Regul Integr Comp Physiol 2011; 300:1352-62
PhenoMaster / LabMaster (Calorimetry, Activity)
Rousso-Noori L, Knobler H, Levy-Apter E, Kuperman Y, Neufeld-Cohen A, Keshet Y, Akepati YR, Klinghoffer RA, Chen A, Elson A
Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner
Cell Metab 2011; 13:562-72
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Schilling S, Kohlmann S, Bäuscher C, Sedlmeier R, Koch B, Eichentopf R, Becker A, Cynis H, Hoffmann T, Berg S, Freyse J, von Hörsten S, Rossner S, Graubner S, Demuth HU
Glutaminyl cyclase (OC) knok out mice show mild hypothyreodism but absence of hypogonadism: implications for enzyme function and drug development
J Biol Chem 2011; 286(16):1-19
Fear Conditioning System, RotaRod, PhenoMaster/PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Scott MM, Williams KW, Rossi J, Lee CE, Elmquist JK
Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice
J Clin Invest 2011; 121(6):2413-21
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Tauriainen E, Luostarinen M, Martonen E, Finckenberg P, Kovalainen M, Huotari A, Herzig KH, Lecklin A, Mervaala E
Distinct effects of calorie restriction and resveratrol on diet-induced obesity and Fatty liver formation
J Nutr Metab 2011; :525094
PhenoMaster / LabMaster (Calorimetry, Drinking / Feeding, Activity)
Verbaeys I, Tolle V, Swennen Q, Zizzari P, Buyse J, Epelbaum J, Cokelaere
Schedules feeding results in adipogenesis and increased acylated ghrelin
Am J Physiol Endocrinol Metab 2011; 300:
PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Vernia S, Heredia M, Criado O, Rodriguez de Cordoba S, Garcia-Roves PM, Cansell C, Denis R, Luquet S, Foufelle F, Ferre P, Sanz P
Laforin, a dual specificity phosphatase involved in lafora disease, regulates insulin response and whole-body energy balance in mice
Hum Mol Genet 2011; 20(13):2571-84
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Veyrat-Durebex C, Poher AL, Caillon A, Montet X, Rohner-Jeanrenaud F
Alterations in lipid metabolism and thermogenesis with emergence of brown adipocytes in white adipose tissue in diet-induced obesity-resistant Lou/C rats
Am J Physiol Endocrinol Metab 2011; 300:1146-57
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Wellner N, Tsuboi K, Madsen AN, Holst B, Diep TA, Nakao M, Tokumura A, Burns MP, Deutsch DG, Ueda N, Hansen HS
Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice
Biochim Biophys Acta 2011; 1811:508-12
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Wong KE, Kong J, Zhang W, Szeto FL, Ye H, Deb DK, Brady MJ, Chun Li Y
Targeted expression of human vitamin D receptor in adipocytes decreases energy expenditure and induces obesity in mice
J Biol Chem 2011; 286(39):33804-10
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Zizzari P, Hassouna R, Longchamps R, Epelbaum J, Tolle V
Meal anticipatory rise in acylated ghrelin at dark onset is blunted after long-term fasting in rats
J Neuroendocrinol 2011; 23:804-14
PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Boy J, Schmidt T, Schumann U, Grasshoff U, Unser S, Holzmann C, Schmitt I, Karl T, Laccone F, Wolburg H, Ibrahim S, Riess O
A transgenic mouse model of spinocerebellar ataxia type 3 resembling late disease onset and gender-specific instability of CAG repeats
Neurobiol Dis 2010; 37:284-93
VideoMot, RotaRod, PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Czyzyk TA, Nogueiras R, Lockwood JF, McKinzie JH, Coskun T, Pintar JE, Hammond C, Tschöp MH, Statnick MA
o-Opioid receptors control the metabolic response to a high-energy diet in mice
FASEB J 2010; 24:1151-59
PhenoMaster / LabMaster(Feeding, Activity, Calorimetry)
Dietrich MO, Antunes C, Geliang G, Liu ZW, Borok E, Nie Y, Xu AW, Souza DO, Gao Q, Diano S, Gao XB, Horvath TL
Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity
J Neurosci 2010; 30(35):11815-11825
PhenoMaster / LabMaster (Calorimetry, Feeding, Activity)
Glier MB, Pissios P, Babich SL, Macdonald MLE, Hayden MR, Maratos-Flier E, Gibson WT
The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone
Peptides 2010; 31:123-29
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Labonté ED, Pfluger PT, Cash JG, Kuhel DG, Roja JC, Magness DP, Jandacek RJ, Tschöp MH, Hui DY
Postprandial lysophospholipid suppresses hepatic fatty acid oxidation: the molecular link between group 1B phospholipase A2 and diet-induced obesity
FASEB J 2010; 24:2516-24
PhenoMaster / LabMaster(Drinking / Feeding, Activity, Calorimetry)
Li X, Cope MB, Johnson MS, Smith DL Jr, Nagy TR
Mild calorie restriction induces fat accumulation in female C57BL/6J mice
Obesity 2010; 18(3):456-462
PhenoMaster / LabMaster (Calorimetry, Feeding, Activity)
Lin HV, Plum L, Ono H, Gutiérrez-Juárez R, Shanabrough M, Borok E, Horvath TL, Rossetti L, Accili D
Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor on agouti-related protein and POMC neurons
Diabetes 2010; 59:337-46
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Mauer J, Chaurasia B, Plum L, Quast T, Hampel B, Blüher M, Kolanus W, Kahn CR, Brüning JC
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance
PLOS Genetics 2010; 6(5):e1000938
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Ngai YF, Quong WL, Glier MB, Glavas MM, Babich SL, Innis SM, Kieffer TJ, Gibson WT
Ldlr-/- mice display decreased susceptibility to Western-type diet-induced obesity due to increased thermogenesis
Endocrin 2010; 151(11):5226-36
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Sassmann A, Offermanns S, Wettschureck N
Tamoxifen-inducible Cre-mediated recombination in adipocytes
Genesis 2010; 48:618-625
PhenoMaster / LabMaster (Calorimetry, Feeding, Activity)
Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, Zierler KA, Radner FPW, Eichmann TO, Kienesberger PC, Eder S, Lass A, Haemmerle G, Alsted TJ, Kiens B, Hoefler G, Zechner R, Zimmermann R
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids
J Lipid Res 2010; 51(3):490-9
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, Zierler KA, Radner FPW, Eichmann TO, Kienesberger PC, Eder S, Lass A, Haemmerle G, Alsted TJ, Kiens B, Hoefler G, Zechner R, Zimmermann R
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids
J Lipid Res 2010; 51(3):490-9
PhenoMaster (Calorimetry, Feeding, Activity)
Song Y, Altarejos J, Goodarzi MO, Inoue H, Guo X, Berdeaux R, Kim JH, Goode J, Igata M, Paz JC, Hogan MF, Singh PK, Goebel N, Vera L, Miller N, Cui J, Jones MR, CHARGE Consortium, GIANT Consortium, Chen YDI, Taylor KD, Hsueh WA, Rotter JI, Montminy M
CRTC3 links catecholamine signalling to energy balance
Nature 2010; 468:933-41
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Sutanto MM, Ferguson KK, Sakuma H, Ye H, Brady MJ, Cohen RN
The silencing mediator of retinoid and thyroid hormone receptors (SMRT) regulates adipose tissue accumulation and adipocyte insulin sensitivity in vivo
J Biol Chem 2010; 285(24):18485-95
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Ye R, Jung DY, Jun JY, Li J, Luo S, Ko HJ, Kim JK, Lee AS
Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance
Diabetes 2010; 59:6-16
PhenoMaster / LabMaster(Calorimetry, Drinking, Activity)
Day JW, Ottaway N, Patterson JT, Gelfanov V, Smiley D, Gidda J, Findeisen H, Bruemmer D, Drucker DJ, Chaudhary N, Holland J, Hembree J, Abplanalp W, Grant E, Ruehl J, Wilson H, Kirchner H, Lockie SH, Hofmann S, Woods SC, Nogueiras R, Pfluger PT, Perez-Tilve D, DiMarchi R, Tschöp MH
A novel glucagon and GLP-1 co-agonist eliminates obesity in rodents
Nat Chem Biol 2009; 5(10):749-57
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Edelsbrunner ME, Herzog H, Holzer P
Evidence from knockout mice that peptide YY and neuropeptide Y enforce murine locomotion, exploration and ingestive behaviour in a circadian cycle- and gender-dependent manner
Behav Brain Res 2009; 203:97-107
PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Edelsbrunner ME, Painsipp E, Herzog H, Holzer P
Evidence from knockout mice for distinct implications of neuropeptide-Y Y2 and Y4 receptors in the circadian control of locomotion, exploration, water and food intake
Neuropeptides 2009; 43(6):491-7
PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, Brüning JC, Rüther U
Inactivation of the FTO gene protects from obesity
Nature 2009; 458(7240):894-8
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Kilpeläinen M, Riikonen J, Vlasova MA, Huotari A, Lehto VP, Salonen J, Herzig KH, Järvinen K
In vivo delivery of a peptide, ghrelin antagonist, with mesoporous silicon microparticles
2009; 137:166-70
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Miinalainen IJ, Schmitz W, Huotari A, Autio KJ, Soininen R, Ver Loren van Themaat E, Baes M, Herzig KH, Conzelmann E, Hiltunen K
Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis
PLoS Genetics 2009; 5(7):e1000543
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Nogueiras R, Perez-Tilve D, Veyrat-Durebex C, Morgan DA, Varela L, Haynes WG, Patterson JT, Disse E, Pfluger PT, Lopez M, Woods SC, DiMarchi R, Dieguez C, Rahmouni K, Rohner-Jeanrenaud F, Tschöp MH
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity
J Neurosci 2009; 29(18):5916-25
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Plum L, Lin HV, Dutia R, Tanaka J, Aizawa KS, Matsumoto M, Kim AJ, Cawley NX, Paik JH, Loh YP, DePinho RA, Wardlaw SL, Accili D
The obesity susceptibility gene Carboxypeptidase E links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake
Nat Med 2009; 15(10):1195-201
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Stratigopoulos G, LeDuc CA, Matsuoka N, Gutman R, Rausch R, Robertson SA, Myers MG, Chung WK, Chua SC, Leibel RL
Functional consequences of the human leptin receptor (LEPR) Q223R transversion
Obesity 2009; 17(1):126-35
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Wong KE, Szeto FL, Zhang W, Ye H, Kong J, Zhang Z, Sun XJ, Li YC
Involvement of the vitamin D receptor in energy metabolism: regulation of uncoupling proteins
Am J Physiol Endocrinol Metab 2009; 296(4):E820-8
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Banks A, Kon N, Knight C, Matsumoto M, Gutiérrez-Juárez R, Rossetti L, Gu W, Accili D
SirT1 gain of function increases energy efficiency and prevents diabetes in mice
Cell Metabolism 2008; 8(4):333-41
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Bode FJ, Stephan M, Suhling H, Pabst R, Straub RH, Raber KA, Bonin M, Nguyen HP, Riess O, Bauer A, Sjoberg C, Petersén A, von Hörsten S
Sex differences in a transgenic rat model of Huntington’s disease: decreased 17ß-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males
Hum Mol Genet 2008; 17(17):2595-609
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry), RotaRod
Foryst-Ludwig A, Clemenz M, Hohmann S, Hartge M, Sprang C, Frost N, Krikov M, Bhanot S, Barros R, Morani A, Gustafsson JA, Unger T, Kintscher U
Metabolic actions of estrogen receptor beta (Erb) are mediated by a negative cross-talk with PPARy
PLoS Genetics 2008; 4(6):e1000108
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Hofmann SM, Perez-Tilve D, Greer TM, Coburn BA, Grant E, Basford JE, Tschöp MH, Hui DY
Defective Lipid Delivery Modulates Glucose Tolerance and Metabolic Response to Diet in Apolipoprotein E-Deficient Mice
Diabetes 2008; 57:5-12
PhenoMaster / LabMaster(Drinking / Feeding, Activity, Calorimetry)
Painsipp E, Wultsch T, Edelsbrunner ME, Tasan RO, Singewald N, Herzog H, Holzer P
Reduced anxiety-like and depression-related behavior in neuropeptide Y Y4 receptor knockout mice
Genes Brain Behav 2008; 7(5):532-42
VideoMot, PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Pfluger PT, Herranz D, Velasco S, Serrano M, Tschöp MH
Sirt1 protects against high-fat diet-induced metabolic damage
PNAS 2008; 105(28):9793-8
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Pfluger PT, Kirchner H, Günnel S, Schrott B, Perez-Tilve D, Fu S, Benoit SC, Horvath T, Joost HG, Wortley KE, Sleeman MW, Tschöp MH
Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure
Am J Physiol Gastrointest Liver Physiol 2008; 294(3):G610-8
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Pilvi TK, Seppännen-Laakso T, Simolin H, Finckenberg P, Huotari A, Herzig KH, Korpela R, Oresic M, Mervaala EM
Metabolic changes in fatty liver can be modified by dietary protein and calcium during energy restriction
WJG 2008; 14(28):4462-72
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Reed JA, Benoit SC, Pfluger PT, Tschöp MH, D’Alessio DA, Seeley RJ
Mice with chronically increased circulating ghrelin develop age-related glucose intolerance
Am J Physiol Endocrinol Metab 2008; 294:E752-60
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Strassburg S, Anker SD, Castaneda TR, Burget L, Perez-Tilve D, Pfluger PT, Nogueiras R, Halem H, Dong JZ, Culler MD, Datta R, Tschöp MH
Long-term effects of ghrelin and ghrelin receptor agonists on energy balance in rats
Am J Physiol Endocrinol Metab 2008; 295(1):E78-84
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Cho YR, Kim HJ, Park SY, Ko HJ, Hong EG, Higashimori T, Zhang Z, Jung DY, Ola MS, Lanoue KF, Leiter EH, Kim JK
Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes
Am J Physiol Endocrinol Metab 2007; 293:E327-36
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Hofmann SM, Zhou L, Perez-Tilve D, Greer T, Grant E, Wancata L, Thomas A, Pfluger PT, Basford JE, Gilham D, Herz J, Tschöp MH, Hui DY
Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice
J Clin Invest 2007; 117:3271-82
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Hong EG, Jung DY, Ko HJ, Zhang Z, Ma Z, Jun JY, Kim JH, Summer AD, Vary TC, Gardner TW, Bronson SK, Kim JK
Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling
Am J Physiol Endocrinol Metab 2007; 293(6):1687-96
PhenoMaster / LabMaster(Calorimetry, Feeding / Drinking, Activity)
Nogueiras R, Pfluger P, Tovar S, Myrtha A, Mitchell S, Morris A, Perez-Tilve D, Vazquez MJ, Wiedmer P, Castaneda TR, Dimarchi R, Tschop M, Schurmann A, Joost HG, Williams LM, Langhans W, Dieguez C
Effects of obestatin on energy balance and growth hormone secretion in rodents
Endocrinology 2007; 148(1):21-6
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O’Rahilly S, Rohner-Jeanrenaud F, Tschöp MH
The central melanocortin system directly controls peripheral lipid metabolism
J Clin Invest 2007; 117:3475-88
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Nomiyama T, Perez-Tilve D, Ogawa D, Gizard F, Zhao Y, Heywood EB, Jones KL, Kawamori R, Cassis LA, Tschöp MH, Bruemmer D
Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice
J Clin Invest 2007; 117:2877-88
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Painsipp E, Wultsch T, Shahbazian A, Edelsbrunner M, Kreissl MC, Schirbel A, Bock E, Pabst MA, Thoeringer CK, Huber HP, Holzer P
Experimental gastritis in mice enhances anxiety in a gender-related manner
Neuroscience 2007; 150:522-36
VideoMot, PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Biebermann H, Castaneda TR, van Landeghem F, von Deimling A, Escher F, Brabant G, Hebebrand J, Hinney A, Tschöp MH, Grüters A, Krude H
A role for beta-melanocyte-stimulating hormone in human body-weight regulation
Cell Metab 2006; 3:141-6
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Kampe J, Wiedmer P, Pfluger PT, Castaneda TR, Burget L, Mondala H, Kerr J, Liaw C, Oldfield BJ, Tschöp MH, Bagnol D
Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat
Brain Research 2006; 1119(1):133-49
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Sanna B, Brandt EB, Kaiser RA, Pfluger P, Witt SA, Kimball TR, van Rooij E, De Windt LJ, Rothenberg ME, Tschop MH , Benoit SC, Molkentin JD
Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo
PNAS 2006; 103:7327-32
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Theander-Carrillo C, Wiedmer P, Cettour-Rose P, Nogueiras R, Perez-Tilve D, Pfluger P, Castaneda TR, Muzzin P, Schurmann A, Szanto I, Tschop MH, Rohner-Jeanrenaud F
Ghrelin action in the brain controls adipocyte metabolism
J Clin Invest 2006; 116:1983-93
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry, ), ActiMot, RotaRod, Startle Response
Deblon N, Veyrat-Durebex C, Bourgoin L, Caillon A, Bussier AL, Petrosino S, Piscitelli F, Legros JJ, Geenen V, Foti M, Wahli W, Di Marzo V, Rohner-Jeanrenaud F
Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats
PhenoMaster / LabMaster (Feeding / Drinking, Activity)
Hollis JH, Jonaidi H, Lemus M, Oldfield BJ
The endocannabinoid Arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression
J Neuroimmunol 2011; 233:127-34
PhenoMaster / LabMaster (Calorimetry, Metabolic PhenoCage, Drinking / Feeding, Activity)
Hübener J, Vauti F, Funke C, Wolburg H, Ye Y, Schmidt T, Wolburg-Buchholz K, Schmitt I, Gardyan A, Drießen S, Arnold HH, NguyenHP, Riess O
N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation
Brain 2011; 134:1925-42
PhenoMaster / LabMaster (Drinking / Feeding, Activity), RotaRod
Jamieson PM, Cleasby ME, Kuperman Y, Morton NM, Kelly PAT, Brownstein DG, Mustard KJ, Vaughan JM, Carter RN, Hahn CN, Hardie DG, Seckl JR, Chen A, Vale WW
Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet
Diabetologia 2011; 54:2392-403
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Lin HV, Ren H, Samuel VT, Lee HY, Lu TY, Shulman GI, Accili D
Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues
Diabetes 2011; 60, 3:700-708
PhenoMaster / LabMaster (Calorimetry, Feeding, Activity)
Pfluger PT, Castaneda TR, Heppner KM, Strassburg S, Kruthaupt T, Chaudhary N, Halem H, Culler MD, Datta R, Burget L, Tschöp MH, Nogueiras R, Perez-Tilve D
Ghrelin, peptide YY and their hypothalamic targets differentially regulate spontaneous physical activity
Physiol Behav 2011; 105:52-61
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Ravussin Y, Gutman R, Diano S, Shanabrough M, Borok E, Sarman B, Lehmann A, LeDuc CA, Rosenbaum M, Horvarth TL, Leibel RL
Effects of chronic weight perturbation on energy homeostasis and brain structure in mice
Am J Physiol Regul Integr Comp Physiol 2011; 300:1352-62
PhenoMaster / LabMaster (Calorimetry, Activity)
Rousso-Noori L, Knobler H, Levy-Apter E, Kuperman Y, Neufeld-Cohen A, Keshet Y, Akepati YR, Klinghoffer RA, Chen A, Elson A
Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner
Cell Metab 2011; 13:562-72
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Schilling S, Kohlmann S, Bäuscher C, Sedlmeier R, Koch B, Eichentopf R, Becker A, Cynis H, Hoffmann T, Berg S, Freyse J, von Hörsten S, Rossner S, Graubner S, Demuth HU
Glutaminyl cyclase (OC) knok out mice show mild hypothyreodism but absence of hypogonadism: implications for enzyme function and drug development
J Biol Chem 2011; 286(16):1-19
Fear Conditioning System, RotaRod, PhenoMaster/PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Scott MM, Williams KW, Rossi J, Lee CE, Elmquist JK
Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice
J Clin Invest 2011; 121(6):2413-21
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Tauriainen E, Luostarinen M, Martonen E, Finckenberg P, Kovalainen M, Huotari A, Herzig KH, Lecklin A, Mervaala E
Distinct effects of calorie restriction and resveratrol on diet-induced obesity and Fatty liver formation
J Nutr Metab 2011; :525094
PhenoMaster / LabMaster (Calorimetry, Drinking / Feeding, Activity)
Verbaeys I, Tolle V, Swennen Q, Zizzari P, Buyse J, Epelbaum J, Cokelaere
Schedules feeding results in adipogenesis and increased acylated ghrelin
Am J Physiol Endocrinol Metab 2011; 300:
PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Vernia S, Heredia M, Criado O, Rodriguez de Cordoba S, Garcia-Roves PM, Cansell C, Denis R, Luquet S, Foufelle F, Ferre P, Sanz P
Laforin, a dual specificity phosphatase involved in lafora disease, regulates insulin response and whole-body energy balance in mice
Hum Mol Genet 2011; 20(13):2571-84
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Veyrat-Durebex C, Poher AL, Caillon A, Montet X, Rohner-Jeanrenaud F
Alterations in lipid metabolism and thermogenesis with emergence of brown adipocytes in white adipose tissue in diet-induced obesity-resistant Lou/C rats
Am J Physiol Endocrinol Metab 2011; 300:1146-57
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Wellner N, Tsuboi K, Madsen AN, Holst B, Diep TA, Nakao M, Tokumura A, Burns MP, Deutsch DG, Ueda N, Hansen HS
Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice
Biochim Biophys Acta 2011; 1811:508-12
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Wong KE, Kong J, Zhang W, Szeto FL, Ye H, Deb DK, Brady MJ, Chun Li Y
Targeted expression of human vitamin D receptor in adipocytes decreases energy expenditure and induces obesity in mice
J Biol Chem 2011; 286(39):33804-10
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Zizzari P, Hassouna R, Longchamps R, Epelbaum J, Tolle V
Meal anticipatory rise in acylated ghrelin at dark onset is blunted after long-term fasting in rats
J Neuroendocrinol 2011; 23:804-14
PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Boy J, Schmidt T, Schumann U, Grasshoff U, Unser S, Holzmann C, Schmitt I, Karl T, Laccone F, Wolburg H, Ibrahim S, Riess O
A transgenic mouse model of spinocerebellar ataxia type 3 resembling late disease onset and gender-specific instability of CAG repeats
Neurobiol Dis 2010; 37:284-93
VideoMot, RotaRod, PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Czyzyk TA, Nogueiras R, Lockwood JF, McKinzie JH, Coskun T, Pintar JE, Hammond C, Tschöp MH, Statnick MA
o-Opioid receptors control the metabolic response to a high-energy diet in mice
FASEB J 2010; 24:1151-59
PhenoMaster / LabMaster(Feeding, Activity, Calorimetry)
Dietrich MO, Antunes C, Geliang G, Liu ZW, Borok E, Nie Y, Xu AW, Souza DO, Gao Q, Diano S, Gao XB, Horvath TL
Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity
J Neurosci 2010; 30(35):11815-11825
PhenoMaster / LabMaster (Calorimetry, Feeding, Activity)
Glier MB, Pissios P, Babich SL, Macdonald MLE, Hayden MR, Maratos-Flier E, Gibson WT
The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone
Peptides 2010; 31:123-29
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Labonté ED, Pfluger PT, Cash JG, Kuhel DG, Roja JC, Magness DP, Jandacek RJ, Tschöp MH, Hui DY
Postprandial lysophospholipid suppresses hepatic fatty acid oxidation: the molecular link between group 1B phospholipase A2 and diet-induced obesity
FASEB J 2010; 24:2516-24
PhenoMaster / LabMaster(Drinking / Feeding, Activity, Calorimetry)
Li X, Cope MB, Johnson MS, Smith DL Jr, Nagy TR
Mild calorie restriction induces fat accumulation in female C57BL/6J mice
Obesity 2010; 18(3):456-462
PhenoMaster / LabMaster (Calorimetry, Feeding, Activity)
Lin HV, Plum L, Ono H, Gutiérrez-Juárez R, Shanabrough M, Borok E, Horvath TL, Rossetti L, Accili D
Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor on agouti-related protein and POMC neurons
Diabetes 2010; 59:337-46
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Mauer J, Chaurasia B, Plum L, Quast T, Hampel B, Blüher M, Kolanus W, Kahn CR, Brüning JC
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance
PLOS Genetics 2010; 6(5):e1000938
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Ngai YF, Quong WL, Glier MB, Glavas MM, Babich SL, Innis SM, Kieffer TJ, Gibson WT
Ldlr-/- mice display decreased susceptibility to Western-type diet-induced obesity due to increased thermogenesis
Endocrin 2010; 151(11):5226-36
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Sassmann A, Offermanns S, Wettschureck N
Tamoxifen-inducible Cre-mediated recombination in adipocytes
Genesis 2010; 48:618-625
PhenoMaster / LabMaster (Calorimetry, Feeding, Activity)
Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, Zierler KA, Radner FPW, Eichmann TO, Kienesberger PC, Eder S, Lass A, Haemmerle G, Alsted TJ, Kiens B, Hoefler G, Zechner R, Zimmermann R
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids
J Lipid Res 2010; 51(3):490-9
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, Zierler KA, Radner FPW, Eichmann TO, Kienesberger PC, Eder S, Lass A, Haemmerle G, Alsted TJ, Kiens B, Hoefler G, Zechner R, Zimmermann R
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids
J Lipid Res 2010; 51(3):490-9
PhenoMaster (Calorimetry, Feeding, Activity)
Song Y, Altarejos J, Goodarzi MO, Inoue H, Guo X, Berdeaux R, Kim JH, Goode J, Igata M, Paz JC, Hogan MF, Singh PK, Goebel N, Vera L, Miller N, Cui J, Jones MR, CHARGE Consortium, GIANT Consortium, Chen YDI, Taylor KD, Hsueh WA, Rotter JI, Montminy M
CRTC3 links catecholamine signalling to energy balance
Nature 2010; 468:933-41
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Sutanto MM, Ferguson KK, Sakuma H, Ye H, Brady MJ, Cohen RN
The silencing mediator of retinoid and thyroid hormone receptors (SMRT) regulates adipose tissue accumulation and adipocyte insulin sensitivity in vivo
J Biol Chem 2010; 285(24):18485-95
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Ye R, Jung DY, Jun JY, Li J, Luo S, Ko HJ, Kim JK, Lee AS
Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance
Diabetes 2010; 59:6-16
PhenoMaster / LabMaster(Calorimetry, Drinking, Activity)
Day JW, Ottaway N, Patterson JT, Gelfanov V, Smiley D, Gidda J, Findeisen H, Bruemmer D, Drucker DJ, Chaudhary N, Holland J, Hembree J, Abplanalp W, Grant E, Ruehl J, Wilson H, Kirchner H, Lockie SH, Hofmann S, Woods SC, Nogueiras R, Pfluger PT, Perez-Tilve D, DiMarchi R, Tschöp MH
A novel glucagon and GLP-1 co-agonist eliminates obesity in rodents
Nat Chem Biol 2009; 5(10):749-57
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Edelsbrunner ME, Herzog H, Holzer P
Evidence from knockout mice that peptide YY and neuropeptide Y enforce murine locomotion, exploration and ingestive behaviour in a circadian cycle- and gender-dependent manner
Behav Brain Res 2009; 203:97-107
PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Edelsbrunner ME, Painsipp E, Herzog H, Holzer P
Evidence from knockout mice for distinct implications of neuropeptide-Y Y2 and Y4 receptors in the circadian control of locomotion, exploration, water and food intake
Neuropeptides 2009; 43(6):491-7
PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, Brüning JC, Rüther U
Inactivation of the FTO gene protects from obesity
Nature 2009; 458(7240):894-8
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Kilpeläinen M, Riikonen J, Vlasova MA, Huotari A, Lehto VP, Salonen J, Herzig KH, Järvinen K
In vivo delivery of a peptide, ghrelin antagonist, with mesoporous silicon microparticles
2009; 137:166-70
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Miinalainen IJ, Schmitz W, Huotari A, Autio KJ, Soininen R, Ver Loren van Themaat E, Baes M, Herzig KH, Conzelmann E, Hiltunen K
Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis
PLoS Genetics 2009; 5(7):e1000543
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Nogueiras R, Perez-Tilve D, Veyrat-Durebex C, Morgan DA, Varela L, Haynes WG, Patterson JT, Disse E, Pfluger PT, Lopez M, Woods SC, DiMarchi R, Dieguez C, Rahmouni K, Rohner-Jeanrenaud F, Tschöp MH
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity
J Neurosci 2009; 29(18):5916-25
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Plum L, Lin HV, Dutia R, Tanaka J, Aizawa KS, Matsumoto M, Kim AJ, Cawley NX, Paik JH, Loh YP, DePinho RA, Wardlaw SL, Accili D
The obesity susceptibility gene Carboxypeptidase E links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake
Nat Med 2009; 15(10):1195-201
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Stratigopoulos G, LeDuc CA, Matsuoka N, Gutman R, Rausch R, Robertson SA, Myers MG, Chung WK, Chua SC, Leibel RL
Functional consequences of the human leptin receptor (LEPR) Q223R transversion
Obesity 2009; 17(1):126-35
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Wong KE, Szeto FL, Zhang W, Ye H, Kong J, Zhang Z, Sun XJ, Li YC
Involvement of the vitamin D receptor in energy metabolism: regulation of uncoupling proteins
Am J Physiol Endocrinol Metab 2009; 296(4):E820-8
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Banks A, Kon N, Knight C, Matsumoto M, Gutiérrez-Juárez R, Rossetti L, Gu W, Accili D
SirT1 gain of function increases energy efficiency and prevents diabetes in mice
Cell Metabolism 2008; 8(4):333-41
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Bode FJ, Stephan M, Suhling H, Pabst R, Straub RH, Raber KA, Bonin M, Nguyen HP, Riess O, Bauer A, Sjoberg C, Petersén A, von Hörsten S
Sex differences in a transgenic rat model of Huntington’s disease: decreased 17ß-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males
Hum Mol Genet 2008; 17(17):2595-609
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry), RotaRod
Foryst-Ludwig A, Clemenz M, Hohmann S, Hartge M, Sprang C, Frost N, Krikov M, Bhanot S, Barros R, Morani A, Gustafsson JA, Unger T, Kintscher U
Metabolic actions of estrogen receptor beta (Erb) are mediated by a negative cross-talk with PPARy
PLoS Genetics 2008; 4(6):e1000108
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Hofmann SM, Perez-Tilve D, Greer TM, Coburn BA, Grant E, Basford JE, Tschöp MH, Hui DY
Defective Lipid Delivery Modulates Glucose Tolerance and Metabolic Response to Diet in Apolipoprotein E-Deficient Mice
Diabetes 2008; 57:5-12
PhenoMaster / LabMaster(Drinking / Feeding, Activity, Calorimetry)
Painsipp E, Wultsch T, Edelsbrunner ME, Tasan RO, Singewald N, Herzog H, Holzer P
Reduced anxiety-like and depression-related behavior in neuropeptide Y Y4 receptor knockout mice
Genes Brain Behav 2008; 7(5):532-42
VideoMot, PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Pfluger PT, Herranz D, Velasco S, Serrano M, Tschöp MH
Sirt1 protects against high-fat diet-induced metabolic damage
PNAS 2008; 105(28):9793-8
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Pfluger PT, Kirchner H, Günnel S, Schrott B, Perez-Tilve D, Fu S, Benoit SC, Horvath T, Joost HG, Wortley KE, Sleeman MW, Tschöp MH
Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure
Am J Physiol Gastrointest Liver Physiol 2008; 294(3):G610-8
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Pilvi TK, Seppännen-Laakso T, Simolin H, Finckenberg P, Huotari A, Herzig KH, Korpela R, Oresic M, Mervaala EM
Metabolic changes in fatty liver can be modified by dietary protein and calcium during energy restriction
WJG 2008; 14(28):4462-72
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Reed JA, Benoit SC, Pfluger PT, Tschöp MH, D’Alessio DA, Seeley RJ
Mice with chronically increased circulating ghrelin develop age-related glucose intolerance
Am J Physiol Endocrinol Metab 2008; 294:E752-60
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Strassburg S, Anker SD, Castaneda TR, Burget L, Perez-Tilve D, Pfluger PT, Nogueiras R, Halem H, Dong JZ, Culler MD, Datta R, Tschöp MH
Long-term effects of ghrelin and ghrelin receptor agonists on energy balance in rats
Am J Physiol Endocrinol Metab 2008; 295(1):E78-84
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Cho YR, Kim HJ, Park SY, Ko HJ, Hong EG, Higashimori T, Zhang Z, Jung DY, Ola MS, Lanoue KF, Leiter EH, Kim JK
Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes
Am J Physiol Endocrinol Metab 2007; 293:E327-36
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Hofmann SM, Zhou L, Perez-Tilve D, Greer T, Grant E, Wancata L, Thomas A, Pfluger PT, Basford JE, Gilham D, Herz J, Tschöp MH, Hui DY
Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice
J Clin Invest 2007; 117:3271-82
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Hong EG, Jung DY, Ko HJ, Zhang Z, Ma Z, Jun JY, Kim JH, Summer AD, Vary TC, Gardner TW, Bronson SK, Kim JK
Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling
Am J Physiol Endocrinol Metab 2007; 293(6):1687-96
PhenoMaster / LabMaster(Calorimetry, Feeding / Drinking, Activity)
Nogueiras R, Pfluger P, Tovar S, Myrtha A, Mitchell S, Morris A, Perez-Tilve D, Vazquez MJ, Wiedmer P, Castaneda TR, Dimarchi R, Tschop M, Schurmann A, Joost HG, Williams LM, Langhans W, Dieguez C
Effects of obestatin on energy balance and growth hormone secretion in rodents
Endocrinology 2007; 148(1):21-6
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O’Rahilly S, Rohner-Jeanrenaud F, Tschöp MH
The central melanocortin system directly controls peripheral lipid metabolism
J Clin Invest 2007; 117:3475-88
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Nomiyama T, Perez-Tilve D, Ogawa D, Gizard F, Zhao Y, Heywood EB, Jones KL, Kawamori R, Cassis LA, Tschöp MH, Bruemmer D
Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice
J Clin Invest 2007; 117:2877-88
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Painsipp E, Wultsch T, Shahbazian A, Edelsbrunner M, Kreissl MC, Schirbel A, Bock E, Pabst MA, Thoeringer CK, Huber HP, Holzer P
Experimental gastritis in mice enhances anxiety in a gender-related manner
Neuroscience 2007; 150:522-36
VideoMot, PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Biebermann H, Castaneda TR, van Landeghem F, von Deimling A, Escher F, Brabant G, Hebebrand J, Hinney A, Tschöp MH, Grüters A, Krude H
A role for beta-melanocyte-stimulating hormone in human body-weight regulation
Cell Metab 2006; 3:141-6
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Kampe J, Wiedmer P, Pfluger PT, Castaneda TR, Burget L, Mondala H, Kerr J, Liaw C, Oldfield BJ, Tschöp MH, Bagnol D
Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat
Brain Research 2006; 1119(1):133-49
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Sanna B, Brandt EB, Kaiser RA, Pfluger P, Witt SA, Kimball TR, van Rooij E, De Windt LJ, Rothenberg ME, Tschop MH , Benoit SC, Molkentin JD
Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo
PNAS 2006; 103:7327-32
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry)
Theander-Carrillo C, Wiedmer P, Cettour-Rose P, Nogueiras R, Perez-Tilve D, Pfluger P, Castaneda TR, Muzzin P, Schurmann A, Szanto I, Tschop MH, Rohner-Jeanrenaud F
Ghrelin action in the brain controls adipocyte metabolism
J Clin Invest 2006; 116:1983-93
PhenoMaster / LabMaster (Drinking / Feeding, Activity, Calorimetry, ), ActiMot, RotaRod, Startle Response
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Comprehensive system for measuring the behavioral parameters of animals: the consumption of food, drink, locomotor, conditioning. This allows to conduct multiple experiments at the same time.