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LifeAct-TagGFP2 Protein-Immediate F-Actin Visualization in Living and Fixed Cells

LifeAct-TagGFP2 Protein-Immediate F-Actin Visualization in Living and Fixed Cells

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F-actin is a key component of the cytoskeleton and is involved in many important cellular processes such as cell division, cell migration, and endocytosis.

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LifeAct-TagGFP2 Protein-Immediate F-Actin Visualization in Living and Fixed Cells


Achieve fast staining and immediate functional analysis of filamentous actin (F-actin) in living and fixed cells with ibidi’s new reagent, LifeAct-TagGFP2 Protein. The addition of this recombinant protein extends the successful ibidi LifeAct product line for F-actin visualization and offers an interesting, non-toxic and non-invasive alternative to phalloidin.
 
F-actin is a key component of the cytoskeleton and is involved in many important cellular processes such as cell division, cell migration, and endocytosis. LifeAct—a 17-amino acid peptide that is derived from a protein found in yeast—specifically binds F-actin structures in living or fixed eukaryotic cells, while uniquely retaining full actin dynamics. Conjugated with GFP, it can be conveniently introduced into cells, making it the ideal tool for F-actin labeling.
 
With LifeAct-TagGFP2 Protein, scientists can easily transfect living cells (e.g., using a protein transfection reagent such as ibidi’s Fuse-It-P), then get brilliant fluorescence microscopy images of cellular F-actin structures within minutes for analysis.
 
LifeAct-TagGFP2 Protein keeps unrestricted actin functionality and does not interfere with cytoskeletal dynamics. This, and the excellent signal-to-noise ratio, make it especially interesting for researchers who investigate the cytoskeletal organization, cellular dynamics, or the function of actin binding proteins using live cell imaging.