Cryopreserved – Please inquire for pricing and availability.
Nomenclature: SD- slc22a8 tm1sage
Genotype: Homozygous
Description: This model contains a biallelic deletion of the organic anion transporter 3 (Oat3), also known as solute carrier family 22 member 8 (SLC22A8). Oat3 plays a central role in renal organic anion transport. Along with Oat1, Oat3 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys- making this a useful model for studying drug-drug interations, toxicity and metabolism in the liver.
Coat color: White, albino.
Strain code: TGRS6510
Bred in: US
