Nomenclature: SD- OPRM1 tm1sage
Genotype: Homozygous
Description: This model possesses an 11 base pair deletion in exon 2 of the Oprm1 gene, leading to an early stop codon in exon 3. Oprm1 encodes the mu opioid receptor 1 (MOR), the major target of most clinically used opioids. This model is useful for applications investigating nociception, and is particularly useful for discrimination among opioid receptor subtypes.
Coat color: White, albino.
Strain code: TGRA8540
Bred in: US