Line Rescue - Charles River

Line Rescue - Charles River

When a unique breeding colony stops producing, a researcher will face a significant challenge when trying to continue their experiment. Our line rescue service can diagnose, plan, and recover these breeding colonies, allowing research and breeding to continue to meet set goals.

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Line Rescue - Charles River

Overview

When a unique breeding colony stops producing, a researcher will face a significant challenge when trying to continue their experiment. Our line rescue service can diagnose, plan, and recover these breeding colonies, allowing research and breeding to continue to meet set goals.

Diagnosis

The first step to rescuing your line is to determine the cause of the reduced or absent breeding performance. We have a variety of tools at our disposal to accomplish this task, including:

Superovulation followed by oocyte collection and analysis to determine female fertility
Computerized sperm analysis to determine male fertility
Observational matings to determine copulation ability
Embryo collection and analysis at various stages to determine if implantation and growth are occurring

Solution

Once the cause and severity of the fertility problem has been assessed, we have several services specifically designed to overcome the issue, including:

  • Foster nursing
  • Ovarian transplantation
  • Artificial insemination
  • Laser-assisted in vitro fertilization (IVF)