RotaMeter TSE Systems



The TSE Rotameter is a computer-controlled system designed to analyze rotations in rodents induced by unilateral brain lesions.

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  • Description
  • Publications


The TSE Rotameter is a computer-controlled system designed to analyze rotations in rodents induced by unilateral brain lesions. The animal, connected to a rotation sensor can move unrestricted in a special unit. This sensor monitors clockwise and counterclockwise rotations with a resolution of 1/250 turn and records changes of directions.

The TSE Rotameter software for Windows allows the adjustment of filter settings to change detection sensitivity according to the specific needs of the user. Experiments can be started and stopped independently in all connected units. The software provides graphical and numerical evaluation of experimental data and export files for further statistics.

Key Features

  • Differently sized animal jackets
  • Bowl-shaped or cylindrical unites made from clear acrylic for optimum visibility
  • Cylindrical test cages made from opaque plastics on request
  • Simultaneous or staggered start – remote control to start the measurement at a distance from the PC
  • Monitor clockwise & counterclockwise rotations with high resolution (1.44°)
  • Easy-to-use USB connection
Greco B, Lopez S, van der Putten H, Flor PJ, Almalric M
Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of parkinson’s disease
J Pharmacol Exp Ther 2010; 332(3):1064-71
Jones CA, Johnston LC, Jackson MJ, Smith LA, van Scharrenburg G, Rose S, Jenner PG, McCreary AC
An in vivo pharmacological evaluation of pardoprunox (SLV308)-a novel combined dopamine D2/D3 receptor partial agonist and 5-HT1A receptor agonist with efficacy in experimental models of Parkinson´s disease
Eur Neuropsychopharmacol 2010; 20:582-93
Vernon AC, Johansson SM, Modo MM
Non-invasive evaluation of nigrostriatal neuropathology in a proteasome inhibitor rodent model of Parkinson´s disease
BMC Neurosci 2010; 11(1):1-18

Grip Strength Meter, Rotameter
Yang JR, Liao CH, Pang CY, Huang LLH, Lin YT, Chen YL, Shiue YL, Chen LR
Directed differentiation into neural lineages and therapeutic potential of porcine embryonic stem cells in rat Parkinson’s disease model
Cell Reprogram 2010; 12(4):447-61
Swistowski A, Peng J, Han Y, Swistowska AM, Rao MS, Zeng X
Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and domaminergic neurons derived from them
PLoS ONE 2009; 4(7):1-11
Schmidt WJ, Lebsaft H, Heindl M, Gerlach M, Gruenblatt E, Riederer P, Mayerhofer A, Scheller DKA
Continuous versus pulsatile administration of rotigotine in 6-OHDA-lesioned rats: contralateral rotations and abnormal involuntary movements
J Neural Transm 2008; 115:1385-92
Valastro B, Dekundy A, Krogh M, Lundblad M, James P, Danysz W, Quack G, Cenci MA
Proteomic analysis of striatal proteins in the rat model of l-DOPA-induced dyskinesia
J Neurochem 2007; 102:1395-1409
Baier PC, Branisa P, Koch R, Schindehutte J, Paulus W, Trenkwalder C
Circadian distribution of motor-activity in unilaterally 6-hydroxy-dopamine lesioned rats
Exp Brain Res 2006; 169:283-8
Stereotaxic Instruments, Rotameter, VideoMot
Lebsanft HB, Kohles T, Kovar KA, Schmidt WJ
3,4-Methylenedioxymethamphetamine counteracts akinesia enantioselectively in rat rotational behavior and catalepsy
Synapse 2005; 55:148-55
Lebsanft HB, Kovar KA, Schmidt WJ
3,4-Methylenedioxymethamphetamine and naloxone in rat rotational behaviour and open field
Eur J Pharmacol 2005; 516:34-9
Rotameter, ActiMot
Srinivasan J, Schmidt WJ
Serotonergic influence on the potentiation of D-amphetamine and apomorphine-induced rotational behavior by the alpha(2)-adrenoceptor antagonist 2-methoxy idazoxan in hemiparkinsonian rats
J Neural Transm 2005; 112(9):1223-36
Baier PC, Schindehutte J, Thinyane K, Flugge G, Fuchs E, Mansouri A, Paulus W, Gruss P, Trenkwalder C
Behavioral changes in unilaterally 6-hydroxy-dopamine lesioned rats after transplantation of differentiated mouse embryonic stem cells without morphological integration
Stem Cells 2004; 22(3):396-404
Grip Strength Meter, Rotameter, Stereotaxic Instruments
Breysse N, Baunez C, Spooren W, Gasparini F, Amalric M
Chronic but not acute treatment with a metabotropic glutamate 5 receprot antagonist reverses the akinetic deficits in a rat model of parkinsonism
J Neurosci 2002; 22(13):5669-78
Meissner W, Harnack D, Paul G, Reum T, Sohr R, Morgenstern R, Kupsch A
Deep brain stimulation of subthalamic neurons increases striatal dopamine metabolism and induces contralateral circling in freely moving 6-hydroxydopamine-lesioned rats
Neurosci Lett 2002; 328:105-8
Modo M, Stroemer RP, Tang E, Patel S, Hodges H
Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage
Stroke 2002; 33(9):2270-8
Reum T, Olshausen F, Mazel T, Vorisek I, Morgenstern R, Sykova E
Diffusion parameters in the striatum of rats with 6-hydroxydopamine-induced lesions and with fetal mesencephalic grafts
J Neurosci Res 2002; 70:680-93
Drandarevski N, Marburger A, Walther D, Reum T, Uhl G, Morgenstern R
Dopaminergic mRNA expression in the intact substantia nigra of unilaterally 6-OHDA-lesioned and grafted rats: an in situ hybridization study
J Neural Transm 2001; 108(2):141-51
Veizovic T, Beech JS, Stroemer RP, Watson WP, Hodges H
Resolution of stroke deficits following contralateral grafts of conditionally immortal neuroepithelial stem cells
Stroke 2001; 32:1012-9
Veizovic T, Beech JS, Stroemer RP, Watson WP, Hodges H
Resolution of stroke deficits following contralateral grafts of conditionally immortal neuroepithelial stem cells
Stroke 2001; 32:1012-9
Spooren WP, Gasparini F, Bergmann R, Kuhn R
Effects of the prototypical mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats
Eur J Pharmacol 2000; 406:403-10
Rotameter, RotaRod
Spooren WP, Waldmeier P, Gentsch C
The effect of a subchronic post-lesion treatment with (-)-deprenyl on the sensitivity of 6-OHDA-lesioned rats to apomorphine and d-amphetamine
J Neural Transm 1999; 106:825-33
Reum T, Morgenstern R
Fetal mesencephalic grafts influence the dopamine release in the non-lesioned striatum of 6-OHDA-lesioned rats: a behavioral and in vivo voltammetric study
Neurosci Lett 1994; 173:172-6