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RotaRod Advanced

Rotarod TSE Systems

RotaRod Advanced

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The TSE RotaRod System is a flexible tool for studying motor coordination or fatigue resistance in rats and mice.

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RotaRod Advanced

The TSE RotaRod System is a flexible tool for studying motor coordination or fatigue resistance in rats and mice. We provide standard models for 5 mice and for 4 rats. The rat unit can also be upgraded with a drum suitable for mice. For obese and / or old rats a model for 3 rats with extra space is available.

Each lane is controlled by its own timer operated independently. Animal falls are detected by light-beam sensors. Motor speed for drum rotation is controlled electronically. Each RotaRod is supplied complete with a control unit that is connected to the PC notebook by a USB interface. A user-friendly Windows software allows to define, store and run automatically speed profiles with up to 100 steps per profile; within each step the initial speed, final speed and acceleration / deceleration time can be defined. All RotaRod units are also equipped with a programmable reverse rotation mode. With its most flexible and unique test protocols, performance differences between animals can be detected that cannot be differentiated by other systems.

Key Features

  • Speed range: 1-60 rpm, constant or accelerating / decelerating
  • Programmable speed profiles with up to 100 individual steps for refined motor skill testing
  • Including reverse rotation feature
  • Optional electric shocker module
  • Extra-high units available if shock reinforcement is not suitable
  • Data export into Excel
Geis C, Weishaupt A, Grünewald B, Wultsch T, Reif A, Gerlach M, Dirkx R, Solimena M, Perani D, Heckmann M, Toyka KV, Folli F, Sommer C
Human stiff-person syndrome lgG induces anxious behavior in rats
PLoS ONE 2011; 6(2):
VideoMot, Elevated Plus Maze, RotaRod
Hübener J, Vauti F, Funke C, Wolburg H, Ye Y, Schmidt T, Wolburg-Buchholz K, Schmitt I, Gardyan A, Drießen S, Arnold HH, NguyenHP, Riess O
N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation
Brain 2011; 134:1925-42
PhenoMaster / LabMaster (Drinking / Feeding, Activity), RotaRod
Schilling S, Kohlmann S, Bäuscher C, Sedlmeier R, Koch B, Eichentopf R, Becker A, Cynis H, Hoffmann T, Berg S, Freyse J, von Hörsten S, Rossner S, Graubner S, Demuth HU
Glutaminyl cyclase (OC) knok out mice show mild hypothyreodism but absence of hypogonadism: implications for enzyme function and drug development
J Biol Chem 2011; 286(16):1-19
Fear Conditioning System, RotaRod, PhenoMaster/PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Geis C, Weishaupt A, Grünewald B, Wultsch T, Reif A, Gerlach M, Dirkx R, Solimena M, Perani D, Heckmann M, Toyka KV, Folli F, Sommer C
Human stiff-person syndrome lgG induces anxious behavior in rats
PLoS ONE 2011; 6(2):
VideoMot, Elevated Plus Maze, RotaRod
Hübener J, Vauti F, Funke C, Wolburg H, Ye Y, Schmidt T, Wolburg-Buchholz K, Schmitt I, Gardyan A, Drießen S, Arnold HH, NguyenHP, Riess O
N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation
Brain 2011; 134:1925-42
PhenoMaster / LabMaster (Drinking / Feeding, Activity), RotaRod
Schilling S, Kohlmann S, Bäuscher C, Sedlmeier R, Koch B, Eichentopf R, Becker A, Cynis H, Hoffmann T, Berg S, Freyse J, von Hörsten S, Rossner S, Graubner S, Demuth HU
Glutaminyl cyclase (OC) knok out mice show mild hypothyreodism but absence of hypogonadism: implications for enzyme function and drug development
J Biol Chem 2011; 286(16):1-19
Fear Conditioning System, RotaRod, PhenoMaster/PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Boy J, Schmidt T, Schumann U, Grasshoff U, Unser S, Holzmann C, Schmitt I, Karl T, Laccone F, Wolburg H, Ibrahim S, Riess O
A transgenic mouse model of spinocerebellar ataxia type 3 resembling late disease onset and gender-specific instability of CAG repeats
Neurobiol Dis 2010; 37:284-93
VideoMot, RotaRod, PhenoMaster / LabMaster (Drinking / Feeding, Activity)
Kim S, Lehtinen MK, Sessa A, Zappaterra M, Cho SH, Gonzalez D, Boggan B, Austin CA, Wijnholds J, Gambello MJ, Malicki J, LaMantina AS, Broccoli V, Walsh CA
The apical complex couples cell fate and cell survival to cerebral cortical development
Neuron 2010; 66(1):69-84
RotaRod
Konopka W, Kiryk A, Novak M, Herwerth M, Parkitna JR, Wawrzyniak M, Kowarsch A, Michaluk P, Dzwonek J, Arnsperger T, Wilczynski G, Merkenschlager M, Theis FJ, Köhr G, Kaczmarek L, Schütz G
MicroRNA loss enhances learning and memory in mice
J Neurosci 2010; 30(44):14835-42
IntelliCage Mouse, RotaRod
Nuber S, Franck T, Wolburg H, Schumann U, Casadei N, Fischer K, Calaminus C, Pichler BJ, Chanarat S, Teismann P, Schulz JB, Luft AR, Tomuik J, Wilbertz J, Bornemann A, Krüger R, Riess O
Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alternations in mice
Neurogenetics 2010; 11(1):107-20
RotaRod
Pacelli C, Coluccia A, Grattagliano I, Cocco T, Petrosilli G, Paradies G, De Nitto E, Massaro A, Persichella M, Borracci P, Portincasa P, Carratù MR
Dietary choline deprivation impairs rat brain mitochondrial function and behavioral phenotype
J Nutr 2010; :1072-9
RotaRod