IntelliCage for mice
IntelliCage allows normal social behavior of mice and respects animal welfare. Your mice will act and react more naturally in an undisturbed environment while living in their normal social circle – increasing the quality and comparability of your data while minimizing your effort!
Key features
- fully automated screening for behavioral and cognitive functions of mice living in social groups in a home cage equipped with 4 programmable operant corners
- transponder technology permits assessment of individual performance
- high level of standardization achieved by minimizing human disturbance and performing automated monitoring
- allows uninterrupted short- or long-term monitoring
- permits investigators to focus on mechanistic analysis of detected effects
- animal friendly: group living reduces "stereotypes", more natural behavior can be observed
- user friendly software modules: no detailed behavioral know-how necessary
- IntelliCage for Rats using the same proven technology
- AnimalGate for individually controlled access to new arenas
- SocialBox for the monitoring of social interactions in mice
- AudioBox for acoustic conditioning in connection with a home cage
IntelliCage functionality
IntelliCage Webinar Clip: "How to Investigate Behavior and Cognitive Abilities of Individual Rodents in a Social Group"
2020IntelliCage as a tool for measuring mouse behavior – 20 years perspective Anna Kiryk, Artur Janusz, Bartosz Zglinicki, Emir Turkes, Ewelina Knapska, Witold Konopka, Hans-Peter Lipp,Leszek Kaczmarek 2014Early deprivation induces competitive subordinance in C57BL/6 male mice. Benner S, Endo T, Endo N, Kakeyama M, Tohyama C. Frequency Tuning in the Behaving Mouse: Different Bandwidths for Discrimination and Generalization. de Hoz L, Nelken I. Early life stress in fathers improves behavioural flexibility in their offspring. Gapp K, Soldado-Magraner S, Alvarez-Sánchez M, Bohacek J, Vernaz G, Shu H, Franklin TB, Wolfer D, Mansuy IM. Kulesskaya N, Karpova NN, Ma L, Tian L, Voikar V. The role of carbonic anhydrase VI in bitter taste perception: evidence from the Car6−/− mouse model. Patrikainen M, Pan P, Kulesskaya N, Voikar V, Parkkila S. Puscian A, Lęski S, Górkiewicz T, Meyza K, Lipp HP, Knapska E. A Model of Alcohol Drinking under an Intermittent Access Schedule Using Group-Housed Mice. Smutek M, Turbasa M, Sikora M, Piechota M, Zajdel J, Przewlocki R, Parkitna JR. Too LK, Ball HJ, McGregor IS, Hunt NH. Too LK, McQuillan JA, Ball HJ, Kanai M, Nakamura T, Funakoshi H, McGregor IS, Hunt NH. Urbach YK, Raber KA, Canneva F, Plank AC, Andreasson T, Ponten H, Kullingsjö J, Nguyen HP, Riess O, von Hörsten S.
Spontaneous behavior in the social homecage discriminates strains,lesions and mutations in mice. Vannoni E, Voikar V, Colacicco G, Sánchez MA, Lipp HP, Wolfer DP. 2013
Learning and memory with neuropathic pain: impact of old age and progranulin deficiency. Albuquerque B, Häussler A, Vannoni E, Wolfer DP, Tegeder I. Branchi I, Santarelli S, Capoccia S, Poggini S, D’Andrea I, Cirulli F, Alleva E. Kalm M, Karlsson N, Nilsson MK, Blomgren K. Knapska E, Lioudyno V, Kiryk A, Mikosz M, Górkiewicz T, Michaluk P, Gawlak M, Chaturvedi M, Mochol G, Balcerzyk M, Wojcik DK, Wilczynski GM, Kaczmarek L. Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice. Kobayashi Y, Sano Y, Vannoni E, Goto H, Suzuki H, Oba A, Kawasaki H, Kanba S, Lipp HP, Murphy NP, Wolfer DP, Itohara S. CD73 is a major regulator of adenosinergic signalling in mouse brain. Kulesskaya N, Võikar V, Peltola M, Yegutkin GG, Salmi M, Jalkanen S, Rauvala H. Ogi H, Itoh K, Fushiki S. Transplantation of enteric neural stem/progenitor cells into the irradiated young mouse hippocampus. Osman AM, Zhou K, Zhu C, Blomgren K. Parkitna JR, Sikora M, Gołda S, Gołembiowska K, Bystrowska B, Engblom D, Bilbao A, Przewlocki R. Ryan D, Koss D, Porcu E, Woodcock H, Robinson L, Platt B, Riedel G. Too LK, Ball HJ, McGregor IS, Hunt NH. Voikar V, Kulesskaya N, Laakso T, Lauren J, Strittmatter SM, Airaksinen MS. 2012
Codita A, Mohammed AH, Willuweit A, Reichelt A, Alleva E, Branchi I, Cirulli F, Colacicco G, Voikar V, Wolfer DP, Buschmann FJ, Lipp HP, Vannoni E, Krackow S. Endo T, Kakeyama M, Uemura Y, Haijima A, Okuno H, Bito H, Tohyama C. Huo K, Sun Y, Li H, Du X, Wang X, Karlsson N, Zhu C, Blomgren K. Jedynak P, Jaholkowski P, Wozniak G, Sandi C, Kaczmarek L, Filipkowski RK Characterization of an alcohol addiction-prone phenotype in mice. Radwanska K, Kaczmarek L. Ramakers GJ, Wolfer D, Rosenberger G, Kuchenbecker K, Kreienkamp HJ, Prange-Kiel J, Rune G, Richter K, Langnaese K, Masneuf S, Bösl MR, Fischer KD, Krugers HJ, Lipp HP, van Galen E, Kutsche K. Roughton K, Kalm M, Blomgren K. 2011Automated test of behavioral flexibility in mice using a behavioral sequencing task in IntelliCage Endo T, Maekawa F, Võikar V, Haijima A, Uemura Y, Zhan Y, Miyazaki W, Suyama S, Shimazaki K, Wolfer DP, Yada T, Tohyama C, Lipp HP, Kakeyama |
|
Ermakova O, Piszcek L, Luciani L, Cavalli FMG, Ferreira T, Farley D, Rizzo S, Paolicelli RC, Al-Banchaabouchi M, Nerlov C, Moriggl R, Luscombe NM, Gross C |
|
Faizi M, Bader PL, Tun C, Encarnacion A, Kleschevnikov A, Belichenko P, Saw N, Priestley M, Tsien RW, Mobley WC, Shamloo M |
|
Karlsson N, Kalm M, Nilsson MK, Mallard C, Björk-Eriksson T, Blomgren K |
|
Kiryk A, Mochol G, Filipkowski RK, Wawrzyniak M, Lioudyno V, Knapska E, Gorkiewicz T, Balcerzsk M, Lemski S, Van Leuven F, Lipp HP, Wójcik DK, Kaczmarek L |
|
Lan WCJ, Priestley M, Mayoral SR, Tian L, Shamloo M, Penn AA |
|
Characterization of an alcohol addiction-prone phenotype in mice Radwanska K, Kaczmarek L |
|
Ramakers GJ, Wolfer D, Rosenberger G, Kuchenbecker K, Kreienkamp HJ, Prange-Kiel J, Rune G, Richter K, Langnaese K, Masneuf S, Bösl MR, Fischer KD, Krugers HJ, Lipp HP, van Galen E, Kutsche K. |
|
Sekiguchi K, Imamura S, Yamaguchi T, Tabuchi M, Kanno H, Terawaki K, Kase Y, Ikarashi Y |
|
d’Isa R, Clapcote SJ, Voikar V, Wolfer DP, Giese KP, Brambilla R, Fasano S |
2010Barlind A, Karlsson N, Björk-Eriksson T, Isgaard J, Blomgren K |
|
Impaired behavior of female tg-ArcSwe APP mice in the IntelliCage: a longitudinal study Codita A, Gumucio A, Lannfelt L, Gellerfors P, Winblad B, Mohammed AH, Nilsson LNG |
|
MicroRNA loss enhances learning and memory in mice Konopka W, Kiryk A, Novak M, Herwerth M, Parkitna JR, Wawrzyniak M, Kowarsch A, Michaluk P, Dzwonek J, Arnsperger T, Wilczynski G, Merkenschlager M, Theis FJ, Köhr G, Kaczmarek L, Schütz G |
|
Consistent behavioral phenotype differences between inbred mouse strains in the IntelliCage Krackow S, Vannoni E, Codita A, Mohammed AH, Cirulli F, Branchi I, Alleva E, Reichelt A, Willuweit A, Voikar V, Colacicco G, Wolfer DP, Buschmann JU, Safi K, Lipp HP |
|
Guidlines for preclinical animal research in ALS/MND: A consensus meeting Ludolph AC, Bendotti C, Blaugrund E, Chio A, Greensmith L, Loeffler JP, Mead R, Niessen HG, Petri S, Pradat PF, Robberecht W, Ruegg M, Schwalenstöcker B, Stiller D, Van Den Berg L, Vieira F, Von Horsten S |
|
Neurobehavioral tests in rat models of degenerative brain diseases Urbach YK, Bode FJ, Jguyen HP, Riess O, von Hörsten S |
|
Voikar V, Colacicco G, Gruber O, Vannoni E, Lipp HP, Wolfer DP |
2009Branchi I, D’Andrea I, Cirulli F, Lipp HP, Alleva E |
|
Jaholkowski P, Kiryk A, Jedynak P, Ben Abdallah NM, Knapska E, Kowalczyk A, Piechal A, Blecharz-Klin K, Figiel I, Lioudyno V, Widy-Tyszkiewicz E, Wilczynski GM, Lipp HP, Kaczmarek L, Filipkowski RK |
|
Mechan AO, Wyss A, Rieger H, Mohajeri MH |
|
Rudenko O, Tkach V, Berezin V, Bock E |
|
Germline expression of H-Ras(G12V) causes neurological deficits associated to Costello syndrome Viosca J, Schuhmacher AJ, Guerra C, Barco A |
|
Zhu C, Gao J, Karlsson N, Li Q, Zhang Y, Huang Z, Li H, Kuhn HG, Blomgren K |
2008A robust automated system elucidates mouse home cage behavioral structure Goulding, EH, Schenk AK, Juneja P, MacKay AW, Wade JM, Tecott LH |
|
Behavioral characterization of GLT1 (+/-) mice as a model of mild glutamatergic hyperfunction. Kiryk A, Aida T, Tanaka K, Banerjee P, Wilczynski GM, Meyza K, Knapska E, Filipkowski RK, Kaczmarek L, Danysz W |
2007Onishchenko N, Tamm C, Vahter M, Hökfelt T, Johnson JA, Johnson DA, Ceccatelli S |
2006Differential involvement of the central amygdala in appetitive versus aversive learning Knapska E, Walasek G, Nikolaev E, Neuhäusser-Wespy F, Lipp HP, Kaczmarek L, Werka T |
|
Safi K, Neuhäusser-Wespy F, Welzl H, Lipp HP |
|
Advanced behavioral screening: automated home cage ethology Spruijt BM, DeVisser L |
2005Galsworthy MJ, Amrein I, Kuptsov PA, Poletaeva II, Zinn P, Rau A, Vyssotski A, Lipp HP |
|
High-throughput and automated behavioral screening of normal and genetically modified mice Lipp HP |
2002Bohannon J |