Danish Myo Technology

Organ Bath System - 720MO

Code 720MOTDMT
Measure & Exlorer Contraction of Smooth Muscle Tissue for the in vitro study of larger vascular smooth muscle (>450μm) and other tubular tissues types.
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Features

The 4-channel Tissue-/Organ Bath System - 720MO is a highly sophisticated, robust, easy-to-use research instrument for the in vitro study of larger blood vessels (>450μm) and other tubular tissues.

Each single tissue bath unit, made of aluminum, has a round, centrally placed stainless steel chamber. The tissue supports are pins positioned in the chamber with one side attached to the force transducer and the other to a micro positioner. 

Each unit has individually controlled gas inflow and suction. Heating and connections for vacuum and gassing are on the myograph interface, permitting the preparations in all four chambers to be kept under physiological conditions (37°C, and bubbled with a gas mixture of your choice).

The interface unit also houses all the electronics and micro-processor for calibration, the circuitry for analog outputs, and a USB port for easy updates on the back. 

With this Tissue Bath System 720MO, the preparations can be stretched until they are exposed to the desired pre-load which will ensure reproducibility among the tissues and between experiments. 

Following mounting and equilibration, passive length-tension relationships for the vessels are determined. During experiments the circumference of the vessel is kept constant. Compounds can be added directly to the chamber, and the tissues’ contractility and reactivity are measured under isometric conditions.

This Tissue Bath System is highly suited for pharmacological investigations of tissue reactivity. Multiple 720MO units, especially in combination with the Buffer Filler System - 625FS, can be conveniently arranged side-by-side, making the 720MO an ideal system for work requiring a higher throughput, such as drug screening, concentration responses, or experiments where individual testing of larger diameter tubular tissues in separate baths is necessary.

Chamber Unit

  • Acid resistent stainless steel chamber (avoid lipids/compounds sticking)
  • Ring-mounted segments <10mm
  • Low chamber volume

Interface Unit

  • Integrated heating, gassing, & drainage
  • Direct data streaming
  • Selectable force range (mN)
  • Intregreted calibration procedure
  • Intuitive touch-screen interface menus
  • Compact design / small footprint