Ugo Basile
Activity Cage for recording of spontaneous coordinate activity in rats and mice
Code 47420UB
Enables recording of spontaneous locomotor activity in rats and mice (individual or groups) using infrared (I.R.) beams. General activity can be an indicator of drug action, toxic substances, neurological damage, or daily rhythms in activity.
Tracks horizontal and vertical activity (rearing). Easily integrated with video-tracking system to measure XY position. Easy touch-buttons, graphic display. High throughput with up to 6 cages monitored by the same electronic unit.
See other products in applications
Features
Background
- Measures horizontal and vertical activity in rats and mice, useful in the following types of investigations:
- General Toxicology for ascertaining the action of a drug
- Psychopharmacology for screening drugs which are potentially active on the CNS
- Behavioral Sciences for evaluating the variations of spontaneous activity after changes in environmental conditions.
Horizontal and vertical movements, complete set up
- Movement is tracked by beam breaks as the animal crosses one or more I.R. beam/s in the cage.
- Horizontal and vertical movements are recorded unobtrusively and saved to the electronic unit (stand-alone controller).
- Easily integrated with video tracking system to measure rearing XY position.
- The I.R. beams are arranged in an array of emitters on one side of the cage, detectors on another. The upper IR array that monitors vertical or rearing activity is height-adjustable.
- The activity data are displayed at pre-set time intervals and printed/routed to the computer according to the selected configuration. The data can be customized by adding animal and experiment numbers, gender, etc.
- The experiment is configured using touch buttons and graphic display.
- Print data in a convenient format using an embedded printer for GLP.
- Customize experiment data by adding animal & experiment numbers, gender, etc.
- The Activity Cage includes:
- Electronic unit with embedded printer
- An animal cage of clear Perspex, 40x40cm
- Two sets of emitter/sensor arrays for horizontal and vertical activity
- Thermal printer
- Serial port, plus serial to USB adaptor, for PC connection
- Software
- Add up to 5 extra cages for high throughput. The electronic unit processes data up to 6 cages.
- Open-field cages are also available in different dimensions and colors. Ask for details.
Features&benefits of activity cage from Ugo Basile
- IR photocells arrays of adjustable height: same instrument for rats and mice
- 2 pairs of IR photocells arrays: measure locomotion and rearing
- Embedded printer, memory and software: GLP compliant, stand-alone or PC-connected
Components
Standard system components
- 7441 Microprocessor controlled electronic unit, for single cage operation
- 7433 Animal cage, including transparent cage, lid, base with supporting rods, catch pan and connection cable
- 7435 Set of horizontal sensors (emitter/receiver), complete with connection cable
- 7436 Set of vertical sensors, (emitter/receiver), complete with connection cable
- 37400-305 Package of 10 heat-sensitive paper rolls (2 rolls are provided)
- 52010-320 USB to serial port converter
- E AU 101 USB key including instruction manual and software
Publications
- Acute and repeated exposure with the nitric oxide (NO) donor sodium nitroprusside (SNP) differentially modulate responses in a rat model of anxiety MA Orfanidou, A Lafioniatis, A Trevlopoulou… - Nitric Oxide, 2017
- Therapeutic effects of aqueous, methanol and ethanol extracts of Egyptian Artemisia herba-alba in STZ-induced diabetic neuropathy in rats SA El-Marasy, ER Zaki, HMI Abdallah, MS Arbid - Journal of Applied Pharmaceutical …, 2017
- HBK-14 and HBK-15 with antidepressant-like and/or memory-enhancing properties increase serotonin levels in the hippocampus after chronic treatment in mice K Pytka, K Gawlik, D Pawlica-Gosiewska, J Witalis… - Metabolic Brain Disease, 2016
- Intranasal Chromium Induces Acute Brain and Lung Injuries in Rats: Assessment of Different Potential Hazardous Effects of Environmental and Occupational … A Salama, R Hegazy, A Hassan - PLOS ONE, 2016
- D. I. Brierley et alia: “Neuromotor Tolerability and Behavioural Characterisation of Cannabidiolic Acid, a Phytocannabinoid with Therapeutic Potential for Anticipatory Nausea” Psychopharmacology 233(2): 243-254, 2016
- P.L. Mikolajczak et alia: “Evaluation of Anti-Inflammatory and Analgesic Activities of Extracts from Herb of Chelidonium Majus L.” Cent Eur J Immunol. 40(4): 400–410, 2015
- A. Marazioti et alia: "Somatostatin Receptors in the Ventral Pallidum/Substantia Innominata Modulate Rat Locomotor Activity" Psychopharmacol., 181:2, 319-326, 2005
- W. Ponti et alia: "In vivo Model for the Evaluation of Molecules Active Towards Transmissible Spongiform Encephalopathies" Veter. Res. Communicat., 28:1, 307-310, 2004
- T. Dolezal et alia: "Guaifenesin Enhances The Analgesic Potency of Paracetamol in Mice” Arch. Pharmacol., 366:6, 551-554, 2002
- M. Votava et alia: "Effects of Alprazolam and Fluoxetine on Morphine Sensitization in Mice” Physiol. Res., 51, 417-423, 2002
