Knowledge Base
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Catheterization - What to do when you need catheterized rodents but you don’t have a surgeon on staff?
Learn more about preconditioned animal models can be delivered to your lab.
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Caging systems - plastic cages for laboratory animals and their exploitation
Plastic cages for laboratory animals are made of polycarbonate and polysulphon. What are the basic properties of these materials, how to wash and sterilize plastic pet cages?
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Caging systems - How many laboratory animals can be maintain in a cage?
Directive 2010/63/EU on the protection of animals used for scientific provides detailed guidelines for the placement of animals in cages of different sizes. View key information about cage size requirements for laboratory animals.
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Caging systems - Allentown's IVC
Why Allentown's Indyvidually Ventilated Cages are distinguished and why are so good?
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Cells - How Automated Counting and Sizing Data make Mammosphere Assays more Practical and Reliable
Mechanisms underlying breast cancer
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Cells - 5 Crucial Steps for Obtaining a Great Immunofluorescent Cell Image
by Shuntaro Yamada, Centre for Translational Oral Research, University of Bergen
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Cells - Mechanistic Insights into Immune Synapse Formation During Immune Response
by Manuel Izquierdo, Departamento de Bioquímica, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain
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Cardiology - Pressure-volume catheter placement in the left ventricle – Carotid vs. Apical approach
Ventricular pressure-volume (PV) relationships are a well established and comprehensive means for assessing cardiac function across a range of animal models.
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Caging systems - Single-use housing system analysis
All the advantages of the single-use EasyCage system
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Genetics - International Genetic Standarization (IGS) Program
Check how Charles River manage outbred and inbred colonies to supply animals to conduct reliable and repeatable research.
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Genetic Quality Control of inbred and F1 hybrid rodent strains
Charles River Inbred Genetic Quality Control Program is the basis of inbred colony management, and the provision of animals for research with a clearly defined genetic lineage.
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Genetics - Strategies to minimize genetic drift and maximize experimental reproducibility in mouse research
How important is genetic stability in mouse research? Read about the best practise and methods in colony management that can be limit genetic drift.
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Genetics - The JAX™ patented Genetic Stability Program (GSP)
Effective prevention of cumulative genetic drift in JAX strains
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Imaging - 3D capture vs. caliper for tumor measurements in laboratory animals
Comparison of measuring subcutaneous tumors with a caliper or Peira scanner.
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Infections - COVID-19 and Cellular Hypoxia
Does hypoxia impact on inhibition of SARS-CoV-2 infection?
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Irradiation - Applications of irradiation in the cell biology laboratory
Development of specialized cell models using irradiation
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Lab animals: Syrian Hamster’s Starring Role in COVID-19 Research
The model has become a ‘golden’ standard’ in researching the pandemic.
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Lab animals - Define “Humanized”
Two Mouse Models Helping Produce Cancer Immunotherapies
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Lab animals: Fighting NASH with a New Animal Model
The Zucker Diabetic Sprague Dawley Rat: A potential game changer for metabolic disease research