CELLS - How to Study Endothelial Cells of The Cardiovascular System In Vitro
Endothelial cells (ECs) are specialized cells that line the inner surface of blood vessels, forming a continuous single-cell layer. They are, therefore, part of the blood vessel wall and play a crucial role in controlling the exchange of substances between the bloodstream and surrounding tissues . ECs are further sub-specialized based on their location in the circulatory system, such as arteries, veins, capillaries, and lymphatics. In this blog article, we explore the functions of ECs, focusing on ECs of the cardiovascular system. Specifically, we will examine how to study ECs in vitro in angiogenesis, barrier formation, under flow, and inflammation.