Type: Inbred mice
Origin: The CBA mouse was developed by Strong in 1920 from a cross between a Bagg albino female and a DBA male. It was introduced into The Jackson Laboratory in 1948 at the F-67 generation and then into Charles River Laboratories France in August 1982 at the F-186 generation. Replacement of the PES in 2005.
This widely used general purpose strain is the only CBA substrain that carries the Pde6brd1 mutation, which causes blindness by wean age. Renal tubulointerstitial lesions have been observed in this strain at a high frequency. Some CBA/J mice spontaneously develop exocrine pancreatic insufficiency syndrome. Research includes immunology and inflammation, metabolism, hearing and cochlear function, infectious disease, and fetal development.
Coat color: Agouti
Strain code: 624
Ideal for: General purpose strain, immunology and inflammation, metabolism, hearing and cochlear function, infectious disease, and fetal development.
JAX™ Stock No: 000656
More information about the strain:
Note: Only The Jackson Laboratory and Charles River in Europe and Japan maintain colonies of JAX™ Mice strains which are derived from pedigreed mice from The Jackson Laboratory and are re-infused routinely with pedigreed mice to stabilise the genetic integrity and phenotype of these strains.
JAX™ is a trademark of The Jackson Laboratory registered in the United States. All rights reserved.
Bred in: France
Health reports: Using strain nomenclature find the strain at links below
*Photos provided courtesy of Charles River