Ugo Basile
Circular pools for Morris water maze test
Code 40105/40125/40155/40185
A test for spatial learning and long-term memory in rodents. For research into neurocognitive disorders and treatments, aging, drug-abuse, neural systems, neurotransmitters and brain development.
High quality, strong and low weight. Embedded wheels for easy movement. Easy to drain and clean. Add optional Atlantis System to extend test capabilities. Different colors available.
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Features
Background of Morris water maze
- “Water maze" test was developed by Richard Morris as a test of spatial learning for rodents. It relies on distal cues to navigate from start locations around the perimeter of an open swimming arena (in opaque water) to locate a submerged escape platform.
- Search-to-platform area determines the degree of reliance on spatial versus non-spatial strategies.
- Use video tracking software for measurements such as total distance swum, thigmotaxis duration, velocity, latency to platform, time spent in quadrants.
High quality, easy to move, easy to clean
- Made with high quality alimentary-grade fiberglass selected for its high strength, durability, low weight and easy cleanability. Easy to move and store pool with embedded wheels.
- Easy to empty. Water drain is positioned below the tank.
- Add optional Atlantis System to enable automated lifting and lowering of platforms for easy operation. Allows continuous testing during removal or repositioning of up to 4 platforms.
- Optional heater/circulator available. Uses anti-rust components. 230V-50Hz only.
- Water mazes are 60cm high (from bottom floor to edge) and are available in the following standard diameters:
- 100cm (mice)
- 120cm (mice)
- 150cm (mice and rats)
- 180cm (rats)
- Custom sizes on request
- Available in white, unless another color is requested (blue, grey, black, etc.).
- Monitor subjects with a video tracking system such as ANY-maze that is placed directly above the water tank as rodents swim.
Components
Extend system with following add-ons
- Remote-controlled Atlantis platforms for Morris water maze
- 40125-010 Basic platform for water maze, H30 cm, circular platform 10 cm diameter
Publications
- Effect of methionine-induced hyperhomocysteinemia on neurodegeneration in experimental conditions B Tóthová, M Kovalská, D Kalenská, A Beňová, 2017
- Very low doses of muscimol and baclofen ameliorate cognitive deficits and regulate protein expression in the brain of a rat model of streptozocin-induced Alzheimer's … V Pilipenko, K Narbute, U Beitnere, J Rumaks… - European Journal of Pharmacology, 2017
- D. Ryan et alia: "Spatial Learning Impairments in PLB1Triple Knock-In Alzheimer Mice are Task-Specific and Age-Dependent" Cellular and molecular life sciences 70(14)): 2603-2619, 2013
- G.M. Rose et alia: "Water Maze Testing to Identify Compounds for Cognitive Enhancement" Current protocols in pharmacology :5-63, 2012
Method paper
- Richard Morris: "Developments of a Water-Maze Procedure for Studying Spatial lEarning in the Rat" Journal of neuroscience methods 11(1): 47-60, 1984
- I.Q. Wihshaw et alia: “The Behavior of the Laboratory Rat: A Handbook with Tests” Oxford Univ. Press: 1, 2004
- R. D’Hooge et alia: "Applications of the Morris Water Maze in the Study of Learning and Memory." Brain research reviews 36(1): 60-90, 2001
- G. Riedel et alia: "Reversible Neural Inactivation Reveals Hippocampal Participation in Several Memory Processes" Nature neuroscience 2(10): 898-905, 1999