DBA/2J mouse (JAX™), DBA/2J
Nomenclature: DBA/2J
Type: Inbred mice
Origin: The DBA mouse is the oldest of all inbred strains. It was developed in 1909 by Little, who, around 1929, divided it into two lines: DBA/1 and DBA/2.
It was introduced into The Jackson Laboratory in 1948 at the F-26th generation, and into Charles River France in February 1982 at the F-140th generation. Replacement of the PES in 1986 and 2005 according to The Jackson Laboratory genetic management system.
DBA/2J is a widely used inbred strain. Some characteristics include low susceptibility to developing atherosclerotic aortic lesions, high-frequency hearing loss, susceptibility to audiogenic seizures, development of progressive eye abnormalities that closely mimic human hereditary glaucoma, and extreme intolerance to alcohol and morphine.
Coat color: Dilute brown
Strain code: 625
Ideal for: Safety and efficacy testing, immunology, audiogenic seizures, glaucoma research.
JAX™ Stock No: 000671
More information about the strain:
Note: Only The Jackson Laboratory and Charles River in Europe and Japan maintain colonies of JAX™ Mice strains which are derived from pedigreed mice from The Jackson Laboratory and are re-infused routinely with pedigreed mice to stabilise the genetic integrity and phenotype of these strains.
JAX™ is a trademark of The Jackson Laboratory registered in the United States. All rights reserved.
Charles River Laboratories is the official distributor of JAX mice in Europe. Click and read more.
Bred in: France
Health reports: Using strain nomenclature find the strain at links below
*Photos provided courtesy of Charles River