Type: Inbred mice
Origin: The DBA mouse is the oldest of all inbred strains. It was developed in 1909 by Little, who, around 1929, divided it into two lines: DBA/1 and DBA/2.
It was introduced into The Jackson Laboratory in 1948 at the F-26th generation, and into Charles River France in February 1982 at the F-140th generation. Replacement of the PES in 1986 and 2005 according to The Jackson Laboratory genetic management system.
DBA/2J is a widely used inbred strain. Some characteristics include low susceptibility to developing atherosclerotic aortic lesions, high-frequency hearing loss, susceptibility to audiogenic seizures, development of progressive eye abnormalities that closely mimic human hereditary glaucoma, and extreme intolerance to alcohol and morphine.
Coat color: Dilute brown
Strain code: 625
Ideal for: Safety and efficacy testing, immunology, audiogenic seizures, glaucoma research.
JAX™ Stock No: 000671
More information about the strain:
Note: Only The Jackson Laboratory and Charles River in Europe and Japan maintain colonies of JAX™ Mice strains which are derived from pedigreed mice from The Jackson Laboratory and are re-infused routinely with pedigreed mice to stabilise the genetic integrity and phenotype of these strains.
JAX™ is a trademark of The Jackson Laboratory registered in the United States. All rights reserved.
Bred in: France
Health reports: Using strain nomenclature find the strain at links below
*Photos provided courtesy of Charles River