Durham Holders for Orofacial Stimulation in Rats

Features

• Correlation thresholds in submandibular (trigeminal) region and hindpaw plantar surface
• Test orofacial nociception using a standard Plantar thermal or mechanical stimulator

Benefits

• A step forward toward multifactorial measurement of pain-related sensitivity in animal research
• The new holders complete the scope of the thermal or mechanical stimulators used for assessing hind paw withdrawal

Application

The Durham Holders have distinct advantages which make them ideal as accessories to the classical Hargreaves test and they represent a step forward toward a multifactorial measurement of pain-related sensitivity in animal research.

Quantification of localized hypersensitivity is common in the clinic, but not in animal experiments.

The holders may appear similar to the classic Broome style animal holder; however, those restrainers are clunky, made of clear acrylic, and do not have stimulus apertures, so they could never be used for this stimulation.

Detailed information on UGO BASILE website.