- High-contrast colors
- Non-reflecting surface
- Ample color selection
- Reasonably rough “warm” surface texture
- Quality materials
- Gives optimal results with any Video-Tracking software
- Guarantees optimal camera view and no glare
- Available in grey (standard), blue, white, black, custom color
- Selected for best rodent comfort, non-slippery
- Reliable and durable mazes, easy to clean and store
The elevated plus-maze test is used as a rodent model of anxiety, and is representative of those tests that are based upon the study of spontaneous behaviour patterns. The model is based on the test animal's aversion to open spaces. In the EPM, this anxiety is expressed by the animal spending more time in the enclosed arms.
The elevated plus maze is a widely used behavioral assay for rodents and it has been validated to assess the anti-anxiety effects of pharmacological agents and steroid hormones, and to define brain regions and mechanisms underlying anxiety-related behavior.
Briefly, rats or mice are placed at the junction of the four arms of the maze, facing an open arm, and entries/duration in each arm are recorded by a video-tracking system and observer simultaneously for 5 min. Other ethological parameters (i.e., rears, head dips and stretched-attend postures) can also be observed.
An increase in open arm activity (duration and/or entries) reflects anti-anxiety behavior.
- Supplemental Information Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission SJ Koo, G Kochlamazashvili, B Rost, D Puchkov… - pdfs.semanticscholar.org
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