Ugo Basile
Hole Board Device according to the Boissier-Simon method
Code 6650UB
Studies natural curiosity and exploration behavior of rodents when confronted with a new environment (head-plunging, or nose-poking stereotype) according to the method devised by Boissier-Simon. For testing effects of psychotropic drugs on exploratory behavior.
The Boards are available with opaque or transparent walls for use with video tracking software. Mouse or rat versions.
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Features
- The test enables the initial exploratory activity of the animal and its variations brought about by psychotropic drugs to be assessed.
- The normal mouse of either gender, when confronted with a new environment, will explore holes in the substrate of its environment by poking its nose in and out of the hole a few times, then move on to the next hole.
- The test can be easily performed. It lasts a few minutes and does not require any previous training of the animal.
Durable, optimized for video tracking hole board system
- Each board has 16 holes and is made of tough, durable grey Perspex.
- Supplied with grey opaque or transparent walls.
- Non-reflective, anti glare, matt finish is optimized for video tracking. It also prevents animals from seeing reflections that may alter their behavior.
- Mouse version is sized 40cm x 40cm and the rat version is 1m x 1m.
- Easy to assemble and clean.
Components
Standard system components
- 6651 Control unit
- 6652 Hole board
- 6653 Dust Cover for the Board
- 6654 Dust Cover for the Control Unit
- 6655 Instruction Manual
Publications
- Involvement of the dopaminergic system in the antidepressant-like effect of the lectin isolated from the red marine alga Solieria filiformis in miceTM Abreu, VS Monteiro, ABS Martins, FB Teles… - International Journal of …, 2017
- The anxiolytic-like effect of 6-styryl-2-pyrone in mice involves GABAergic mechanism of actionEMC Chaves, JER Honório-Júnior, CNS Sousa… - Metabolic Brain Disease, 2017
- C. Castillo-Hernández et alia: "Effect of N-Benzylpiperazine, Its Metabolite N-Benzylethylenediamine, and Its Disubstituted Analogue N,N'-Dibenzylpiperazine on the Acquisition, Formation, and Consolidation of Memory in Mice" Pharmacology 99(5-6): 268-274, 2017
- G. Blake et alia: “Hippocampal α7-Nicotinic Cholinergic Receptors Modulate Memory Reconsolidation: A Potential Strategy for Recovery from Amnesia” Neurobiol. Of Learning and Memory 106: 193-203, 2013
- D Can et alia: “Anti-depressant-like Effect of Vitexin in BALB/c Mice and Evidence for the Involvement of Monoaminergic Mechanisms” Eur. J. Pharmacol. 699 (1-3): 250-257, 2013
- L. Balderal-Lopez et alia: “Toxic rather than Neuropharmacological Effect of Ternstroemia Sylvatica Fruits and Identification of 28-O-[β-l-6-rhamnopyranosyl]-R1-barrigenol as a new Compound with Toxic Effects in Mice” Pharmaceutical Biology 51 (11), 2013
- J.R. Boissier et P. Simon: "Dissociation de deux composantes dans le comportement d’investigation de la souris" Arch. Int. Pharmacodyn. 147, No. 3-4, 385-393, 1964
- J.R. Boissier et P. Simon: "L’utilisation d’une réaction particulière de la souris (méthode de la planche a trous) pur l’étude des médicaments psychotropes" Thérapie XIX: 571-589, 1964