Central Nervous System

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Model for cardiovascular research (atherosclerosis, heart abnormalities, hypercholesterolemiam hypertriglyceridemia, vascular defects).
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The model contains monoallelic deletion of the BDNF gene. Useful in the study of Alzheimer's, depression, pain, nerve growth, loss of memory.
CBA mouse
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Research applications include brain development, neurochemistry and behavioural studies
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Model with deletion of DJ-1 gene plays role in protecting neurons from oxidative stress and cell death. Ideal for Parkinson diseases and dopaminergic cell loss research.
Trpv1 knockout rat
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The model has biallelic TRPV1 gene deletion, which is useful in the study of pain, nociception, analgesia, and thermoregulation.
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Model with expresion of Cre recombinase. For applications in optogenetic, expression and nockout recombined genes and DREADD.