Charles River Laboratories

CD-1® Nude mouse, Crl:CD1-Foxn1nu

Code 24102

CD-1 Nude mice are used in oncology, especially in the study of tumors biology. Also used in transplantology and immunological research.

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Immunology Oncology, cancer

Features

Nomenclature: Crl:CD1-Foxn1^nu

Type: Outbred, Immunodeficient

Origin: Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1^® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.

The control model for the CD-1^® Nude mouse is the CD-1^® Heterozygous mouse.

See Charles River webpage with resources about immunodeficient models: Immunodeficient Mice and Rats

Coat color: Hairless, albino background (Homozygous), White, albino (Heterozygous)

Strain code: 086 (Homozygous), 087 (Heterozygous)

Ideal for: Tumor biology and xenograft research

Bred in: Germany, UK, Italy, US

Health reports: Using strain nomenclature find the strain at links below

Learn more about immudeficient models bred by Charles River.

*Photos provided courtesy of Charles River

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Biochemistry and hematology for CD-1® Nude mouse colonies in North American for 01.2011 – 12.2011

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