Handheld Ultrasonic Homogenizer for Tubes and 96-Well Plates

Handheld Ultrasonic Homogenizer for Tubes and 96-Well Plates

The UP-250 is a portable, multi-functional ultrasonic homogenizer for small-volume sample preparation. Compared with conventional benchtop sonicators, its handheld transducer offers greater flexibility, efficiency and mobility, making it ideal for processing many small samples in sequence – for example in microcentrifuge tubes or 96-well plates.

The instrument is operated via a 4.3-inch touch screen and works in automatic or manual mode, with an optional foot switch for jog-controlled sonication. Ultrasonic time and power are freely adjustable, and the unit provides sample temperature detection and automatic frequency tracking.

Key Features

• Portable design – compact generator and handheld transducer for flexible use
• Two operating modes – automatic and manual, with optional foot switch
• Flexible parameters – adjustable ultrasonic power, pulse and total time
• High throughput – rapid sequential sonication of small tubes and microplate wells
• Safety – over-temperature alarm
• Easy operation – 4.3-inch touch screen

Working Principle

The generator converts mains power into a high-frequency electrical signal that drives a piezoelectric transducer. The resulting mechanical vibration is amplified by a titanium alloy horn and transmitted into the liquid at the probe tip. Rapidly alternating pressure cycles create cavitation bubbles that grow and collapse, generating intense local shear forces and micro-jets. These forces rupture cell walls and membranes, break up agglomerates and accelerate mass transfer and chemical reactions.

Applications of the UP-250 Portable Ultrasonic Homogenizer

• Cell disruption and lysis of small-volume samples
• Emulsification, dispersion and homogenization
• Extraction of natural compounds and degassing
• Preparation of nanomaterials
• Acceleration of chemical reactions and cleaning
• High-throughput processing of samples in 96-well plates and small tubes