Charles River Laboratories

NCI SCID/NCr mouse, CB17/Icr-Prkdcscid/IcrCr

Code NCI SCID

Immunodeficient CB17 mouse, ideal for tumor biology and xenograft research.

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Immunology Oncology, cancer

Features

Nomenclature: CB17/Icr-Prkdc^scid/IcrCr

Type: Inbred, immunodeficient

Origin: SCID mice possess a genetic autosomal recessive mutation Prkdc^scid. Discovered in 1980 by Bosma in C.B-17/Icr mice at Fox Chase Cancer Center. SCID mice show a severe combined immunodeficiency affecting both B and T lymphocytes. They have normal natural killer (NK) cells, macrophages and granulocytes. NCI received this mouse in 1991. To Charles River in 2014.

Note: See our isolator page for available immunocompromised animal housing units.

See Charles River webpage with resources about immunodeficient models: Immunodeficient Mice and Rats

Coat color: White (albino)

Strain code: 561

Ideal for: Tumor biology and xenograft research

Bred in: US

Health reports: Using strain nomenclature find the strain at link below

animals health reports bred in Charles River US

*Photos provided courtesy of Charles River

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Health monitoring of immunodeficient rodents in isolators in North America and Europe

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