Cell Cultivation Under Flow – New Insights and Applications

Certain cells, such as the endothelial cells in blood vessels or renal epithelial cells, are constantly exposed to shear stress in vivo. Experimentally, flow conditioning of the cells is achieved by perfusing medium through cultivation chambers, and by maintaining these flow conditions over a long period of time, lasting from hours, up to days.

This webinar will provide an overview of the function of endothelium as a barrier between the blood stream and the tissue beneath. It will also introduce various perfusion applications and experimental setups. In addition, the physical background of flow systems will be explained, as well as the impact of these factors on cells, regarding morphology, physiology, and function.

Learn more about:

• New applications for the ibidi Pump System, such as:
  - impedance measurements under flow
  - pulsatile and oscillating flow
  - solution exchange
• Physical values that impact cell culture, such as:
  - flow chamber geometry and shear stress
  - influence of surface characteristics
• How to choose a suitable system for your application

Speaker of Cell Cultivation Under Flow – New Insights and Applications Webinar

Helga Wagner, ibidi GmbH

Helga Wagner studied Biology at the University of Regensburg. Since 2008 she has been working in Research & Development of custom specific slides for functional cell based assays at ibidi GmbH. Her focus is on the design and implementation of tube formation assays and flow assays.