Charles River Laboratories

NOD SCID mouse, NOD.CB17-Prkdcscid/NCrCrl

Code 241047

The SCID mutation has been transferred onto a diabetes-susceptible Non-Obese Diabetic (NOD) background.

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Immunology Oncology, cancer

Features

Nomenclature: NOD.CB17-Prkdc^scid/NCrCrl

Type: Congenic, Immunodeficient

Origin: The SCID mutation has been transferred onto a non-obese diabetic background. Animals homozygous for the SCID mutation have impaired T and B cell lymphocyte development. The NOD background additionally results in deficient natural killer (NK) cell function. To Charles River in 2003 from NIH.

See Charles River webpage with resources about immunodeficient models: Immunodeficient Mice and Rats

Coat color: White, albino

Strain code: 394

Ideal for: Tumor biology and xenograft research

Bred in: UK

Health reports: Using strain nomenclature find the strain at links below