BALB/c Nude mouse (JAX™), CByJ.Cg-Foxn1nu/J
Nomenclature: CByJ.Cg-Foxn1nu/J
Type: Immunodeficient, Inbred
Origin: This mutation occurred in 1962 in a colony of albino outbred mice maintained at the Ruchill Hospital in Glasgow. The strain BALB/cByJ-nude was created by repeated backcrosses to move the nude gene onto the BALB/cByJ background.
These mice carry a spontaneous mutation at the Foxn1 locus characterized by abnormal hair growth and defective development of the thymic epithelium.
See Charles River webpage with resources about immunodeficient models: Immunodeficient Mice and Rats
Coat color: Homozygotes: hairless, unpigmented; Heterozygotes: haired, albino
Strain code: 633 (Homozygotes), 657 (Heterozygotes)
Ideal for: Tumor biology and xenograft research
JAX™ Stock No: 000711
More information about the strain:
Note: Only The Jackson Laboratory and Charles River in Europe and Japan maintain colonies of JAX™ Mice strains which are derived from pedigreed mice from The Jackson Laboratory and are re-infused routinely with pedigreed mice to stabilise the genetic integrity and phenotype of these strains.
JAX™ is a trademark of The Jackson Laboratory registered in the United States. All rights reserved.
Charles River Laboratories is the official distributor of JAX mice in Europe. Click and read more.
Bred in: France
Health reports: Using strain nomenclature find the strain at links below
Learn more about immudeficient models bred by Charles River.
*Photos provided courtesy of Charles River
A comprehensive list of publications that utilize NSG™ variant mouse models to advance research.
Click here and read NSG references:
- Humanized NSG
- Oncology NSG
- Onco-Hu NSG
- Immunology
- Infectious disease
- Solid tumors
- Hematological cancers
- Diabetes
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- Miscellaneous
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