NU/NU Nude mouse, Crl:NU-Foxn1nu
Nomenclature: Crl:NU-Foxn1nu
Type: Outbred, Immunodeficient
Origin: This immunodeficient nude mouse originated from NIH and was originally thought to be a BALB/c congenic. It was later determined that it was not inbred and is, therefore, maintained as an outbred and is not associated with any stock or strain. The animal lacks a thymus, is unable to produce T-cells, and is, therefore, immunodeficient.
The control model for the NU/NU nude mouse is the heterozygous NU+ mouse.
See Charles River webpage with resources about immunodeficient models: Immunodeficient Mice and Rats
Coat color: Hairless, albino (Homozygous), White, albino (Heterozygous)
Strain code: 088 (Homozygous), 089 (Heterozygous)
Ideal for: Tumor biology and xenograft research
Bred in: US
Health reports: Using strain nomenclature find the strain at links below
*Photos provided courtesy of Charles River