Charles River Laboratories

SCID Beige mouse, CB17.Cg-PrkdcscidLystbg-J/Crl

Code 241033

This double mutant mouse carries both scid and beige mutations and is improved model for receipt of xenotransplants and for infectious disease studies.

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Immunology Oncology, cancer

Features

Nomenclature: CB17.Cg-Prkdc^scidLyst^bg-J/Crl

Type: Congenic, Immunodeficient

Origin: A congenic mouse that possesses both autosomal recessive mutations SCID (Prkdcscid) and beige (Lystbg). The SCID mutation results in severe combined immunodeficiency affecting both the B and T lymphocytes. The beige mutation results in defective natural killer (NK) cells. This mouse was developed by Croy, et al. at the University of Guelph by an intercross of C.B-17 SCID/SCID to C57BL/6 bg/bg mice. To Charles River in 1993.

See Charles River webpage with resources about immunodeficient models: Immunodeficient Mice and Rats

Coat color: White, albino

Strain code: 250

Ideal for: Tumor biology and xenograft research

Bred in: Germany, UK

Health reports: Using strain nomenclature find the strain at links below

*Photos provided courtesy of Charles River

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Charles River, JAX Disease and immunodeficient animal models flyer EN

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Biochemistry and hematology data for SCID Beige mouse

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