Ultrasonic Homogenizer with Built-In Sample Cooling
The SCIENTZ-650L is an integrated probe-type ultrasonic homogenizer with built-in refrigeration. The generator, transducer, sound-insulated chamber and cooling system are combined in one compact unit, so temperature-sensitive samples can be sonicated at temperatures from −4 °C up to room temperature without any external chiller.
With 650 W of power adjustable in 1% steps and a 6 mm standard probe, it processes samples from 100 µl to 50 ml. A 50 ml cooling adapter is included, and adapters for 0.2 ml to 15 ml tubes are available. The instrument disrupts cells, bacteria, viruses and plant and animal tissues and is equally suited to emulsification, separation, extraction, defoaming, cleaning, nanomaterial preparation and acceleration of chemical reactions.
Key Features
- Built-in refrigeration – −4 °C to room temperature, no external cooling device required
- All-in-one design – generator, transducer and sound-insulated chamber integrated in one compact unit
- Low noise – chassis surrounded by three-dimensional eco-friendly acoustic panels
- Fine power control – ultrasonic power adjustable in 1% steps
- Precise timing – ultrasonic and interval time set with 0.1 s resolution; pulsed and continuous operation with test function
- Programmable – intelligent, programmable ultrasonic protocols
- Safety – overload, over-temperature and time alarms
- Premium materials – TC4 military-grade titanium alloy horn
- Easy cleaning – smooth interior walls; interior lighting
- Electric lifting – remote-controlled transducer lift as standard
Working Principle
The generator converts mains power into a high-frequency electrical signal that drives a piezoelectric transducer. The resulting mechanical vibration is amplified by a titanium alloy horn and transmitted into the liquid at the probe tip. Rapidly alternating pressure cycles create cavitation bubbles that grow and collapse, generating intense local shear forces and micro-jets. These forces rupture cell walls and membranes, break up agglomerates and accelerate mass transfer and chemical reactions.
Applications of the SCIENTZ-650L Integrated Ultrasonic Homogenizer
- Lysis of cells, bacteria and viruses with active sample cooling
- Extraction of heat-sensitive proteins, enzymes and nucleic acids
- Disruption of plant and animal tissues
- Emulsification, dispersion and nanomaterial preparation
- Defoaming, cleaning and acceleration of chemical reactions
- Ultrasonic frequency: 20–25 kHz
- Ultrasonic power: 650 W (1–100%)
- Standard probe: 6 mm
- Optional probes: 2, 3 mm
- Sample volume: 100 µl–50 ml
- Display: 7-inch capacitive touch screen
- Temperature alarm: 0–99.9 °C
- Refrigeration temperature: −4 °C to room temperature
- Cooling adapters: standard: 50 ml; optional: 0.2, 0.5, 2, 5, 10, 15 ml
- Transducer lifting: electric, remote control as standard
- Interior lighting: yes
- Dimensions: 312 × 334 × 620 mm
- Integrated main unit with sound-insulated chamber and refrigeration
- TC4 titanium alloy transducer
- 6 mm probe
- 50 ml cooling adapter
- Remote control
