Viewpoint

ZebraBox - high throughput monitoring system

It is a complete system, designed for the high-throughput analysis of zebrafish larvae in multi-well plates with a total control over the experiment environment.

Read more about product
See other products in applications
Features

ZebraBox is a component of ZebraLab and allows the automated observation and tracking of larval zebrafish, and zebrafish embryos. ZebraBox is capable of analyzing zebrafish larvae in multi-well plates, up to 96 individuals simultaneously.

ZebraBox can revolutionize your research thanks to its scalability: several ZebraBoxes can be installed in parallel, allowing to track even more zebrafish with each ZebraLab system. High throughput analysis is at your fingertips with this state-of-the-art system from ViewPoint.

Versatility and reproducibility are important: ZebraBox is flexible enough to accommodate various protocols using 6, 12, 24, 48 and 96-well plates. Integrated illumination, including infrared, and water flow system provide fully standardized experimental conditions. Long-term monitoring without compromising environmental conditions are within the realm of possibility with ZebraBox.

Total control of the experiment conditions

Controlling the abiotic factors and experiment conditions has always been our main concern. More than 10 years of constant development of the ZebraBox lead to the best zebrafish behavior enclosure available on the market.

External factors can greatly influence behaviors of the fish, and this is why the ZebraBox allows a total control over those factors.

Double anti-vibration systems
The ZebraBox feet and the microplate analysis area are mounted on patented anti-vibration systems, eliminating all external vibration sources (subway, road, people walking by, and other apparatus on the table…).

Cold light control
The ZebraBox lighting system is heat-free. Unlike other systems needing the water flow to cool down the apparatus, the ZebraBox do not heat up, even on very long experiments.

Strong light stimulation
The ZebraBox white light can be controlled very accurately over 100 different intensity levels. Once the ZebraBox door is closed, subjects are sealed in totally dark conditions, all the outside light is blocked from entering the equipment allowing total light control. Simulate day-night transitions for circadian cycle studies, trigger series of flash, create any light sequence you can think of and be in total control of the light conditions.

Temperature control
Since the ZebraBox does not generate any heat, you can very accurately control the water temperature from 12 to 50 degrees. You are able to create heat shocks, and temperature change cycles or just keep a very steady temperature throughout the test.

Direct observation technology
The ZebraBox provide direct access and observation of the subjects at all time, offering the best image quality. Based on NASA mirror technology, the ZebraBox is not limited in resolution, unlike lens or other objects on top of the experimenting area which could cause image distortion, water condensation or interfere with the animal behavior.

Soundproof
The special alloy of which the ZebraBox is made restricts external sounds from disturbing the analyzed subject.

Specifications
  • Start monitoring embryos from 36 hpf 
  • Adapted to all standard microplates (6, 12, 24, 48, 96)
  • Controllable white light source for light conditioning : Circadian cycle, flash and light sequence control
  • Infra-Red backlit plate holder for extreme precision detection of the embryos and larvae
  • Light Heat Control - No heat is generated from the lighting sources, water circulation is not mandatory
  • Water flow system: pool, water input and output for long-term monitoring
  • Large experiment area and optimum air circulation
  • Direct observation of the subjects to avoid image distortion (no lens on top of the microplate)
  • Professional grade digital camera :
    - InfraRed high sensitivity
    - High frame rate up to 60 frames /sec.
    - High image definition
  • Included enhancement to zoom in up to an individual well level
  • Plug and play for an easy installation
  • State of the art integrated analytics
  • One year free on-line update
  • Complete onsite installation, setup and training
  • Technical support one year on site and internet remote support
Components
Extend system with following add-ons
  • Temperature control unit
  • Controllable vibration and sound
  • Noise cacelling chamber
  • Shocker
  • Photomotor response
  • Optogenetic top light
  • High speed camera