Charles River Laboratories

Zucker rat (obese), Crl:ZUC-Leprfa

Code Zucker obese

Outbred, obese Zucker rats have very wide applications in obesity and diabetic research, specially in insulin resistance, glucose intolerance and metabolic syndrome research.

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Cardiovascular Metabolism Obesity, overweight Diabetes

Features

Nomenclature: Crl:ZUC-Lepr^fa

Type: Outbred

Origin: The obese or fatty condition appeared spontaneously in the 13M strain maintained at the Laboratory of Comparative Pathology of Theodore and Lois Zucker in Stow, MA. Research colonies were established at many institutions from this nucleus colony. To Charles River in 1985 from a research colony maintained at a pharmaceutical company.

The control model for the Zucker Rat (Obese) is the Zucker Rat (Lean).

Coat color: Four principal variants: 1. predominantly brown; 2. brown and white; 3. predominantly black; 4. black and white.

Strain codes: 185 (Obese)

Ideal for:Insulin resistance, glucose intolerance, metabolic syndrome, genetic obesity.

Learn more about Charles River's metabolic and cardiovascular disease animal models.