Animal models

We are committed to providing you with high-quality genetically standardized models such as SPF (Specific Pathogen Free) and SOPF (Specific and Opportunistic Pathogen Free) animals which are free of select infectious agents and parasites. The terms SPF and SOPF are mare commonly used in continental Europe while, VAF Plus and VAF Elite are mare recognisable in the UK and North America. 
SPF = VAF Plus and SOPF = VAF Elite; they are based on the same monitoring programmes in terms of agents screened, number and age of animals screened, frequency of testing, and recycling policies. 

Ordering information - Download

Research models, products and services can be ordered with our customer service deparment, via telephone or mail.
Each order must be confirmed.
To do the order processing smoother we encourage to use our ordering form, which is available on your request.

Original Health Reports available online on the following webistes :

Charles River Laboratories - Health Reports 
Jackson Laboratories - Health Reports

NSG mouse  The Jackson Laboratory
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Manufacturer:
Strain for oncology,tumors,virology, immunology, inflammation and autoimmunity research.
129 Mouse
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Model for development of ransgenic/knockout models, large number of unmyelinated axons in lumbar motor roots.
AKR Mouse
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Atherosclerotic model, cancer research, metabolic research, diet-induced obesity.
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Manufacturer:
Indicator installed in the exhaust air ducts in Allentown IVC racks. It allows you to thoroughly detect almost 100% of pathogens present in the rack, without the use of sentinel animals or bedding samples. All collected samples are sent to the PCR analysis in Charles River laboratory.
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Quarantines are often required by animal facilities to screen incoming animals for unwanted pathogens prior to introduction, and often take place either in a designated quarantine space or at a third-party facility. Quarantines can assess the current animals’ health status and safeguard against a potential facility contamination.
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Laboratory rabbit model with the lack of expression of ApoE responsible for the metabolism of lipids. Used to test atherogenesis, atherosclerosis, diabetes research.
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Manufacturer:
Model for cardiovascular research (atherosclerosis, heart abnormalities, hypercholesterolemiam hypertriglyceridemia, vascular defects).
Athymic nude mouse Charles River
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Model for tumor biology and xenograft research. The animal lacks a thymus, is unable to produce T cells, and is therefore immunodeficient.
BALBc mouse
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General multipurpose model, hybridoma development, monoclonal antibody production, infectious diseases.
BALBc nude mouse
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Model for tumor biology and xenograft research.
bcrp rat
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Homozygous knockout BCRP with an increased exposure to BCRPspecific substrates. For applications of drug metabolism research, pharmacodynamics and pharmacokinetics, drug-drug interactions.
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The model contains monoallelic deletion of the BDNF gene. Useful in the study of Alzheimer's, depression, pain, nerve growth, loss of memory.
bdnf rat alzheimers 4
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Knockout the gene encoding the ABC transporter, a critical in exporting pump bile salts.
C57 Mouse Charles River
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General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology.
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Knockout model encoding CAR having effects on induction of cytochrome p450s. It has applications in the study of hepatotoxicity, cholestasis and drug metabolism.
CBA mouse
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Research applications include brain development, neurochemistry and behavioural studies
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General multipurpose model, safety and efficacy testing, aging, pseudopregnancy, surgical model.
cd-1 nude mouse
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Model for tumor biology and xenograft research. The animal lacks a thymus, is unable to produce T cells, and is therefore immunodeficient.
Cotton rat
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Model very sensitive to infectious agents of human origin. Ideal for research into the development of vaccines and gene therapy based on adenoviral vectors.
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Manufacturer:
Diabetes and obesity research, wound healing.
DBA 2NCRL
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Safety and efficacy testing, immunology, audiogenic seizures.
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The integrity of your research is susceptible to compromise in the face of natural disaster, genetic drift, and microbial contamination. Our embryology services ensure that no matter the circumstances, you maintain the ability to access your original stock and keep your research moving forward. These options provide an alternative to maintaining live animals for strains that are not currently being used, but may be needed in the future.
Fox chase CB17
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Control for SCID mice.
FVB
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Transgenic/knockout model development.
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For years, our customers have entrusted us with the breeding and housing of their priceless research models, because they know relying on us to manage and maintain their outsourced colonies allows them to focus on their research. Our knowledgeable project managers are committed to achieving your research goals through regular communication and collaboration with their team. You can be confident that your animals are receiving the ultimate care from our skilled technical staff, and that project tasks will be carried out quickly and efficiently.
GLUT 4 Mouse
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Model for a wide range of diabetes studies.
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Manufacturer:
The severe acute respiratory syndrome (SARS) outbreak at the end of 2002 was a global infectious disease epidemic. According to the World Health Organization (WHO), over 8,000 people were infected and over 700 died worldwide. The culprit causing the epidemic was the SARS coronavirus (SARS-CoV), which is named for the coronal or crown shape on the outer membrane of the virus.
guinea pigs hartley
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General multipurpose research model. Bred in France by Charles River.
HSD11B1 Mouse
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Cortisone regulation model.
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When a unique breeding colony stops producing, a researcher will face a significant challenge when trying to continue their experiment. Our line rescue service can diagnose, plan, and recover these breeding colonies, allowing research and breeding to continue to meet set goals.
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General multipurpose research model. Bred in France by Charles River.
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Crl:MON(Tum) Pochodzenie: Szczep został pozyskany przez Charles RIver z farmy Tumblebrook w 1995 roku. Rederywacja dokonana w 1996 roku. Kod szczepu: 243 Kolor sier...
Mouse The Jackson Laboratory C57BL6J
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Manufacturer:
General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology.
New Zealand
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General multipurpose research model for pharmacology, toxicology and teratology research. Bred in France by Charles River.
NMRI nude
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Nomenklatura: Crl: NMRI-Foxn1nu Hodowla: niekrewniacza Pochodzenie: Pierwsza mysz nude pojawiła się w  kolonii w Virus Laboratory, Ruchill Hospital (Glasgow, UK); (...
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The model has the deleted gene organic anion transporter 3 OAT3. Useful in clinical drug-drug interactions, toxicity and liver metabolism.
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Model with deletion of DJ-1 gene plays role in protecting neurons from oxidative stress and cell death. Ideal for Parkinson diseases and dopaminergic cell loss research.
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Our preconditioning services can help alleviate the space, time, and labor costs involved with refining a model to meet your unique research requirements. Whether you are looking for animals fed a special diet, altered through surgery, or reared to a certain age, Charles River has the state-of-the-art animal facilities, professional animal care, and robust model selection to deliver study-ready animals right to your door.
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Knockout model to study the role of nuclear receptors in the impact of carcinogenic substances, the compounds of xenobiotic metabolism and hepatotoxicity.
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Charles River continually invests in innovations and in sophisticated IVF techniques so animals can be produced more quickly and in greater quantities than with traditional methods.
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Overview Charles River can remove adventitious organisms, such as viruses, bacteria, and parasites, from mice and rats with our rederivation services. Rederived animals ar...
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Charles River helps clients select, customize, create, and maintain the right model for their studies using the latest technologies. Our expert staff can work with you from concept to model creation to deliver the research animals you require for your studies.
Trpv1 knockout rat
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The model has biallelic TRPV1 gene deletion, which is useful in the study of pain, nociception, analgesia, and thermoregulation.
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Model with expresion of Cre recombinase. For applications in optogenetic, expression and nockout recombined genes and DREADD.
Wistar Wu rat
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General multipurpose model for toxicology and aging studies.
Szczury rozwijające cukrzycę typu 2.
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Nomenklatura: ZDF-Leprfa/Crl Hodowla: krewniacza Pochodzenie:  Mutacja pojawiła się w niekrewniaczej koloni szczurów Zucker hodowanych w latach 1974-1975 w laborator...