Charles River Laboratories

CD® (Sprague Dawley) IGS rat, Crl:CD(SD)

Code 241005
Most widely-used oudbred rat in biomedical research including toxicology and pharmacology.
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Features

Nomenclature: Crl:CD(SD)

Type: Outbred rat

Origin: Originated in 1925 by Robert W. Dawley from a hybrid hooded male and a female Wistar rat. To Charles River in 1950 from Sprague Dawley, Inc. In 1991, 8 colonies were selected to form the IGS Foundation Colony. Rederived into an isolator foundation colony in 1997. IGS refers to animals bred using the Charles River International Genetic Standardization Program.

Coat color: White (albino)

Strain code: 001

Ideal for: General multipurpose model, safety and efficacy testing, aging, nutrition, diet-induced obesity, oncology, surgical model

Bred in: Germany, UK, Italy 

Health reports: Using strain nomenclature find the strain at links below

Note: We also offer the CD®(SD)IGS SOPF Rat with a SOPF health profile (bred in Italy and France).

*Photos provided courtesy of Charles River

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CD® IGS rat model information sheet
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International Genetic Standardization (IGS) Program
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Vascular catheter locking solutions in rats: sodium citrate as an alternative to heparin
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Outbred rats datasheet
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Compilation of spontaneous neoplastic lesions and survival in Crl:CD® (SD) rats from control groups - 03.2013
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Histopathology findings in 4-26 week old Crl:CD® (SD) rats - 03.2012
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Clinical laboratory parameters for Crl:CD® (SD) rats - 03.2006
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Compilation of spontaneous neoplastic lesions and survival in Crl:CD® (SD) rats from control group - 03.2004
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Biological reference data on CD(SD) IGS rats - 2002-2003
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Postnatal growth, development, and behavioral/functional evaluation Crl:CD® (SD) IGS BR rats - 03.2002
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Compilation of spontaneous neoplastic lesions and survival in Crl:CD® (SD) BR rats from control groups - 03.2001
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Biological reference data on CD(SD) IGS dats - 2001
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The development and maintenance of the Crl:CD® (SD) IGS BR rat breeding system - 1998
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Spontaneous neoplastic lesions and survival in Crl:CD® (SD) BR rats maintained on dietary restriction - 03.1998
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Historical control data (1992-1994) for developmental and reproductive toxicity studies using the Crl:CD® (SD) BR rat - 03.1996
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Hematology parameters for the Crl:CD® BR rat - 02.1993
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Serum chemistry parameters for the CRL:CD® BR rat - 02.1993
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Spontaneous neoplastic lesions and selected non-neoplastic lesions in the Crl:CD® BR rat - 02.1992
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Spontaneous ophthalmic lesions in the Crl:CD® BR rat - 02.1991
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Clinical pathology data for North American CD® rat colonies for 01.2006 - 12.2011
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Heart rate for male CD® rats fed Purina 5L79 diet (03.2009)
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Animal popular models overview and quality flyer EN, CRL, JAX
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