Isothermal DNA Shearing System for up to 96 Tubes
The SCIENTZ08-IIID disrupts and mixes samples using an isothermal, non-contact method, enabling sterile, ultra-trace fragmentation and chromosome shearing directly through centrifuge tube walls. Tailored for NGS DNA and ChIP sample pretreatment, it delivers high throughput, minimal sample loss and zero cross-contamination for laboratories that process many or precious samples every day.
The ultrasonic transducer is integrated into the water bath, so the entire bath is covered by broad, balanced ultrasonic energy with reduced foaming – unlike probe systems, which act only near the probe tip. Continuous automatic rotation of the tubes further improves energy uniformity, and a portable compressor-cooled thermostat keeps samples at a constant temperature between 2 and 40 °C. DNA can be fragmented down to approx. 200 bp.
Key Features
- Non-contact, closed-tube processing – no cross-contamination or aerosols, enhanced biosafety
- Isothermal operation – compressor-cooled thermostat, 2–40 °C, 0.1 °C resolution
- High throughput – up to 96 × 0.1/0.2 ml tubes per run, plus racks for 0.5–15 ml tubes
- 4.3-inch medical-grade touch screen – displays parameters, time, temperature and power
- Smart storage – up to 50 experimental protocols
- Low noise – below 55 dB
- Safety – overcurrent, overvoltage and over-temperature alarms
- Flexible operation – intermittent and continuous modes, continuously adjustable time and power
Applications of the SCIENTZ08-IIID DNA Shearing System
- DNA fragmentation for next-generation sequencing (NGS)
- Chromatin immunoprecipitation (ChIP) sample preparation
- Animal cell disruption
- Protein and inclusion body extraction
- Emulsification
- Food industry, agricultural, forestry and bioengineering research
- Tube types: 0.1–15 ml
- Display: 4.3-inch medical-grade resistive touch screen
- Displayed parameters: operating parameters, time, temperature, power
- Operating mode: pulsed or continuous
- Total ultrasonic time: 0.1 s–9999 min
- Working time: 0.1–99.9 s
- Interval time: 0–99.9 s (0 = continuous)
- Power adjustment: 1–100%
- Ultrasonic tank: 300 × 150 × 100 mm
- Sample volume: from 5 µl to above 2 ml
- Standard adapters: 32 × 0.1/0.2 ml (3 sets), 20 × 0.5/0.65 ml (3 sets)
- Maximum throughput: 32 × 0.1/0.2 ml × 3, 20 × 0.5/0.65 ml × 3, 12 × 1.5/2 ml × 3, 5 × 5–15 ml × 3
- Adapter material: 316 stainless steel
- Noise level: < 55 dB
- Cooling system: portable thermostat (compressor cooling), 600 W cooling capacity
- Temperature range: 2–40 °C, resolution 0.1 °C
- Program storage: 50 protocols
- Alarms: overcurrent, overvoltage, over-temperature
- Ultrasonic main unit with water bath
- Portable thermostat with compressor cooling
- 3 sets of 32 × 0.1/0.2 ml adapters
- 3 sets of 20 × 0.5/0.65 ml adapters
