TRIO™-235, 3-axis / 0–90° Diagonal Micromanipulator

TRIO™-235 — 3-Axis / 0–90° Diagonal Motorized Micromanipulator (In Vivo)

The TRIO™-235 from Sutter Instrument is purpose-built for in vivo electrophysiology work. It replaces the conventional Z-axis with a mechanically adjustable diagonal axis whose angle is set by a set screw (0–90°). This configuration — pairing a traditional X and Y axis with a true physical diagonal axis — gives 50 mm of travel in the diagonal direction and 25 mm in X and Y. Software creates a synthetic Z-axis by combining the diagonal and X axes in reverse, allowing the familiar 3-axis control paradigm.

Key Features

• 3 independent axes: 25 mm travel on X and Y; 50 mm travel on adjustable diagonal axis
• True mechanical diagonal axis: Angle set by set screw (0–90°) — ideal for stereotaxic in vivo approaches
• Synthetic Z-axis: Software combines diagonal and X axes to present a standard 3-axis interface
• Lead-screw precision design: Same precision bearing and lead-screw as TRIO-245; compact footprint
• Motor powers down during recording: Eliminates motor heat and electrical noise — the quietest manipulators in the industry
• Zero drift: Ensures experimental stability throughout long recording sessions
• Integrated ROE controller: No rack-mounted controller required; minimal bench footprint
• Logarithmic acceleration: Smooth, proportional speed control from the ROE knobs
• WORK and HOME memory positions: Rapid, reproducible pipette repositioning
• Universal mounting: Compatible with the most popular headstages and pipette holders
• DIP switch directionality: Easily adapt ROE knob direction to user preference
• Dual voltage: 115/230 V, 50/60 Hz; CE certified

Applications

• In vivo extracellular and intracellular recording
• Stereotaxic brain probe insertion
• In vivo patch clamp
• Any application where a diagonal approach angle is defined by anatomy