Monitoring home cage activity 24H/7D - InfraMot

Monitoring home cage activity 24H/7D - InfraMot


Software controlled instrument for register total animal's activity based on sensing the heat radiating from the animal's body. Ideal for experiments in any light conditions.

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Monitoring home cage activity 24H/7D - InfraMot

The TSE InfraMot system is designed to register total activity of one or more animals under any lighting condition by reliably sensing the heat radiating from the animal’s body and its displacement over time - making it ideally suited for long-term circadian studies. The sensor assembly is designed to be mounted on top of a home cage, but it can also be configured for any other arena such as an operant cage.

As an integral part of our modular PhenoMaster/LabMaster research platform, the InfraMot units can also be combined and synchronized with the measurement of numerous physiological and behavioral parameters such as liquid & food consumption, wheel running behavior or/and metabolic performance.

Key features

  • activity measurements under any lighting condition even complete darkness
  • reliable detection even of subtle movements lasting few milliseconds
  • the wide-angle sensor allows incorporation of rearing events into the activity data
  • simple setup and readout
  • parallel measurement in a large number of home cages
  • no calibration required

2014        2013        2012        2011         2010

2009        2008        2007        2004




Mapping pathological phenotypes in a mouse model of CDKL5 disorder.

Amendola E, Zhan Y, Mattucci C, Castroflorio E, Calcagno E, Fuchs C, Lonetti G, Silingardi D, Vyssotski AL, Farley D, Ciani E, Pizzorusso T, Giustetto M, Gross CT.
PLoS One 2014; 9(5):e91613

Chronic blockade of angiotensin AT1 receptors improves cardinal symptoms of metabolic syndrome in diet-induced obesity in rats.

Müller-Fielitz H, Hübel N, Mildner M, Vogt FM, Barkhausen J, Raasch W. 
Br J Pharmacol 2014; 171(3): 746-6




Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for thetreatment of insomnia.

Betschart C, Hintermann S, Behnke D, Cotesta S, Fendt M, Gee CE, Jacobson LH, Laue G, Ofner S, Chaudhari V, Badiger S, Pandit C, Wagner J, Hoyer D.
J Med Chem 2013; 56(19): 7590-607

Effects of systemic administration of oxytocin on contextual fear extinction in a rat model of post-traumatic stress disorder.

Eskandarian S, Vafaei AA, Vaezi GH, Taherian F, Kashefi A, Rashidy-Pour A.
Basic Clin Neurosci 2013; 4(4):37-44

An Interval of the Obesity QTL Nob3.38 within a QTL Hotspot on Chromosome 1 Modulates Behavioral Phenotypes.

Vogel H, Montag D, Kanzleiter T, Jonas W, Matzke D, Scherneck S, Chadt A, Töle J, Kluge R, Joost HG, Schürmann A. 
PLoS One 2013; 8(1):e53025




Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction.

Finley LW, Lee J, Souza A, Desquiret-Dumas V, Bullock K, Rowe GC, Procaccio V, Clish CB, Arany Z, Haigis MC.
Proc Natl Acad Sci USA 2012; 109(8): 2931-6

Cofilin-1: a modulator of anxiety in mice.

Goodson M, Rust MB, Witke W, Bannerman D, Mott R, Ponting CP, Flint J.
Plos One 2012; 8(10): e1002970

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis.

He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, Korsmeyer S, Packer M, May HI, Hill JA, Virgin HW, Gilpin C, Xiao G, Bassel-Duby R, Scherer PE, Levine B.
Nature 2012; 481(7382): 511-5

The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors.

Mang GM, Dürst T, Bürki H, Imobersteg S, Abramowski D, Schuepbach E, Hoyer D, Fendt M, Gee CE.
Sleep 2012; 35(12): 1625-35

Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin.

Mosienko V, Bert B, Beis D, Matthes S, Fink H, Bader M, Alenina N.
Transl Psychiatry 2012; 2: e122

Site- specific genetic manipulation of amygdala corticotropin- releasing factor reveals its imperative role in mediating behavioral response to challenge.

Regev L, Tsoory M, Gil S, Chen A.
Biol Psychiatry 2012; 71(4): 317-26

Effects of neonatal overfeeding on juvenile and adult feeding and energy expenditure in the rat.

Stefanidis A, Spencer SJ.
PloS one 2012; 7(12): e52130

An anxiolytic role for CRF receptor type 1 in the globus pallidus.

Sztainberg Y, Kuperman Y, Justice N, Chen A.
J Neurosci 2012; 31(48): 17416-17424




microRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34.

Haramati S, Navon I, Issler O, Ezra-Nevo G, Gil S, Zwang R, Hornstein E, Chen A ES.
J Neurosci 2011; 31(40): 14191-14203

Genetic ablation of cGMP-dependent protein kinase type I causes liver inflammation and fasting hyperglycemia.

Lutz SZ, Hennige AM, Feil S, Peter A, Gerling A, Machann J, Kröber SM, Rath M, Schürmann A, Weigert C, Häring HU, Feil R.
Diabetes 2011; 60(5): 1566-76

Inflammation modulates anxiety in an animal model of multiple sclerosis.

Pergua I, Hartwig S, Thöne J, Hovemann B, Gold R, Juckel G, Linker RA.
Behav Brain Res 2011; 220: 20-9

Site-specific genetic manipulation of amygdala corticotropin-releasing factor reveals its imperative role in mediating behavioral response to challenge.

Regev L, Tsoory M, Gil S, Chen A.
Biol Psychiatry 2011; 71(4): 317-26

Resilience to chronic stress is mediated by hippocampal brain-derived neurotrophic factor.

Taliaz D, Loya A, Gersner R, Haramati S, Chen A, Zangen A.
J Neurosci 2011; 31(12): 4475-4483




Intestinal tumours, colonic butyrate and sleep in exercised min mice.

Basterfield L, Mathers JC.
Br J Nutr 2010; 104: 355-63

Overfeeding-induced obesity in spontaneously hypertensive rats: an animal model of the human metabolic syndrome.

Miesel A, Müller H, Thermann M, Heidbreder M, Dominiak P, Raasch W.
Ann Nutr Metab 2010; 56: 127-42

A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery.

Neufeld-Cohen A, Tsoory MM, Evans AK, Getselter D, Gil S, Lowry CA, Vale WW, Chen A.
Proc Natl Acad Sci 2010; 104 (44): 19020-19025

Prolonged and site-specific over-expression of corticotropin-releasing factor reveals differential roles for extended amygdala nuclei in emotional regulation.

Regev L, Neufeld-Cohen A, Tsoory M, Kuperman Y, Getselter D, Gil S, Chen A.
Mol Psychiatry 2010; 16: 714-728

Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1.

Sabio G, Cavanagh-Kyros J, Barrett T, Jung DY, Ko HJ, Ong H, Morel C, Mora A, Reilly J, Kim JK, Davis RJ.
Genes Dev 2010; 24(3): 256-64

Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced induced by a western diet.

Song H, Wohltmann M, Bao S, Ladenson JH, Semenkovich CF, Turk J.
Am J Physiol Endocrinol Metab 2010; 298(6): 1097-114

The anxiolytic effect of environmental enrichment is mediated via amygdala CRF receptor type 1.

Sztainberg Y, Kuperman Y, Tsoory M, Lebow M, Chen A.
Mol Psychiatry 2010; 15(9): 905-17

Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis.

Taliaz D, Stall N, Dar DE, Zangen A. 
Mol Psychiatry 2010; 15: 80-92




Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by Lypd6.

Darvas M, Morsch M, Racz I, Ahmadi S, Swandulla D, Zimmer A.
Eur Neuropsychopharmacol 2009; 19(9): 670-81

Vaccination as a novel approach for treating depressive behavior.

Lewitus GM, Wilf-Yarkoni A, Ziv Y, Shabat-Simon M, Gersner R, Zangen A, Schwartz M.
Biol Psychiatry 2009; 65: 283-8

Increased novelty-induced motor activity and reduced depression-like behavior in neuropeptide Y (NPY)-Y4 receptor knockout mice.

Tasan RO, Lin S, Hetzenauer A, Singewald N, Herzog H, Sperk G.
Neuroscience 2009; 158: 1717-1730




ICV leptin effects on spontaneous physical activity and feeding behavior in rats.

Choi YH, Li C, Hartzell, DL, Little DE, Della-Fera MA, Baile CA.
Behav Brain Res 2008; 188(1): 100-8

Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance.

Jayasooriya AP, Mathai ML, Walker LL, Begg DP, Denton DA, Cameron-Smith D, Egan GF, McKinley MJ, Rodger PD, Sinclair AJ, Wark JD, Weisinger HS, Jois M, Weisinger RS.
Proc Natl Acad Sci USA 2008; 105: 6531-6

Effects of morphine dependence on the performance of rats in reference and working versions of the water maze.

Miladi Gorji H, Rashidy-Pour A, Fathollahi Y.
Physiol Behav 2008; 93: 622-7

Deletion of glucose transporter GLUT8 in mice increases locomotor activity.

Schmidt S, Gawlik V, Hölter SM, Augustin R, Scheepers A, Behrens M, Wurst W, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Kluge R, Joost HG, Schürmann A.
Behav Genet 2008; 38: 396-406

Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice.

Schmidt S, Richter M, Montag D, Sartorius T, Gawlik V, Hennige AM, Scherneck S, Himmelbauer H, Lutz SZ, Augustin R, Kluge R, Ruth P, Joost HG, Schürmann A.
Am J Physiol Endocrinol Metab 2008; 295(5): e1084-94

Regulatory mechanisms of fear extinction and depression-like behavior.

Tronson NC, Schrick C, Fischer A, Sananbenesi F, Pagès G, Pouysségur J, Radulovic J.
Neuropsychopharmacology 2008; 33: 1570-83




Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behavior.

Boyl PP, Di Nardo A, Mulle C, Sassoè-Pognetto, Panzanelli P, Mele A, Kneussel M, Constantini V, Perlas E, Massimi M, Vara H, Giustetto M, Witke W.
EMBO J 2007; 26(12): 2991-3002

Sensitivity of ob/ob mice to leptin-induced adipose tissue apoptosis.

Della-Fera MA, Choi YH, Hartzell DL, Duan J, Hamrick M, Baile CA.
Obes Res 2005; 13(9): 1540-7

Noradrenaline transmission within the ventral bed nucleus of the stria terminalis is critical for fear behavior induced by trimethylthiazoline, a component of fox odor.

Fendt M, Siegl S, Steiniger-Brach B.
J Neurosci 2005; 25(25): 5998-6004

CB1 receptor antagonist AVE1625 affects primarily metabolic parameters independently of reduced food intake in Wistar rats.

Herling AW, Gossel M, Haschke G, Stengelin S, Kuhlmann J, Müller G, Schmoll D, Kramer W.
Am J Physiol Endocrinol Metab 2007; 293: e826-32




Reduced anxiety-related behaviour in transgenic mice overexpressing serotonin 1A receptors.

Kusserow H, Davies B, Hörtnagl H, Voigt I, Stroh T, Bert B, Deng DR, Fink H, Veh RW, Theuring F.
Mol Brain Res 2004; 129: 104-16

The effects of acute restraint stress and dexamethasone on retrieval of long-term memory in rats: an interaction with opiate system.

Rashidy-Pour A, Sadeghi H, Taherain AA, Vafaei AA, Fathollahi Y. 
Behav Brain Res 2004; 154: 193-8

Genetic functional inactivation of neuronal nitric oxide synthase affects stress-related Fos expression in specific brain regions.

Salchner P, Lubec G, Engelmann M, Orlando GF, Wolf G, Sartori SB, Hoeger H, Singewald N. 
Cell Mol Life Sci 2004; 61(12): 1498-506


  • University of Berlin
  • University of Frankfurt
  • University of Leipzig
  • University of Tuebingen


  • University of Innsbruck


  • European Molecular Biology Laoratory - EMBL, Monterotondo - Scalo (RM)


  • Novartis Pharma AG, Basel

Great Britain

  • University of Aberdeen
  • The Rowett Research Institute, Aberdeen


  • University of Semnan


  • Weizmann Institute of Science,m Rehovot

South Korea

  • Korea Research Institute of Chemical Tehcnology - KRICT, Daejeon


  • Physio-Tech Co., Ltd., Tokyo


  • Abbbott Laboratories, Abbott Park, IL
  • University of Athens, GA