Porsolt swim test

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Porsolt swim test

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The forced swim test (also known as Porsolt test or behavioral despair test) is a well-characterized paradigm to analyze depression-like behavior in rodents.

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Porsolt swim test

The forced swim test (also known as Porsolt test or behavioral despair test) is a well-characterized paradigm to analyze depression-like behavior in rodents. It is therefore often used to measure the effects of antidepressant drugs.

As was originally established in rats, in a pretest the animal is made to swim in a water bath from which it cannot escape. During the test session, the amount of time spent immobile is measured and is taken as a measure of hopelessness, or behavioral despair in the animal. TSE Systems offers VideoMot2 system to analyze the motility behavior of swimming animals.

 Key features

  • Antidepressant drug screening
  • Automated recording and analyzing of animal activity
  • Reanalyze data after the experiment has been finished
  • Complete access to raw data
  • Parallel storage of digital files

A related paradigm is the tail suspension test.

Wicke KM, Rex A, Jongen-Relo A, Groth I, Gross G
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants
Psychopharmacology 2007; 195:95-102
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Video tracking system for automated recording and analyzing animal activity in a variety and unlimited of arenas and maze systems.