Radial maze

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Radial maze


The TSE Radial Mazes are completely computerized systems used to investigate hippocampus-dependent learning and memory performance.

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  • Publications

Radial maze

The TSE Radial Mazes are completely computerized systems used to investigate hippocampus-dependent learning and memory performance. In the usual task food is available at the end of each arm or in selected arms only. The animal has to learn to visit each arm without going back to an already-visited empty arm or entering an arm that has never been baited. Learning and memory impairments will influence the performance in subsequent retention tests.

In the Radial Maze software a variety of control parameters can be defined including the start position, termination criterion, feeding pattern, or whether the animal is to be confined in the center to prevent perseverative behavior (only if automatic doors are present). The number of correct choices, i.e. first entries into baited arms, as well as performance errors are calculated. The maze can also be run with non-baited arms or using the continuous refilling option to monitor the locomotion pattern in the maze.

The TSE Radial Maze is also available as a non-automated system for use in the TSE PhenoTracker or the TSE VideoMot2system.

Key Features

  • Evaluation of spatial learning & memory performance in mice & rats
  • Working & reference memory can be tested in one task
  • Infrared sensors monitor transfers between compartments and food removal from food containers
  • Optional automatic pellet feeders & motorized doors
  • Optional acrylic wall material & low wall height configurations to facilitate visibility of extra-maze cues

Daniel JM, Hulst JL, Berbling JL
Estradiol replacement enhances working memory in middle-aged rats when initiated immediately after ovariectomy but not after a long-term period of ovarian hormone deprivation
Endocrinology 2006; 147(1):607-14
Radial Maze
Nguyen HP, Kobbe P, Rahne H, Worpel T, Jager B, Stephan M, Pabst R, Holzmann C, Riess O, Korr H, Kantor O, Petrasch-Parwez E, Wetzel R, Osmand A, von Horsten S
Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington’s disease
Hum Mol Genet 2006; 15:3177-94
RotaRod, Elevated Plus Maze, Radial Maze, Active Avoidance
Scattoni ML, Adriani W, Calamandrei G, Laviola G, Ricceri L
Long-term effects of neonatal basal forebrain cholinergic lesions on radial maze learning and impulsivity in rats
Behav Pharmacol 2006; 17(5-6):517-24
Radial Maze
Becker A, Eyles DW, McGrath JJ, Grecksch G
Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult rats
Behav Brain Res 2005; 161:306-12
Active Avoidance, Radial Maze, ActiMot
Von Hoersten S et al.
Transgenic rat model of Huntington´s disease
Hum Mol Genet 2003; 12(6):617-24
Elevated Plus Maze, Radial Maze, RotaRod
Hoelscher C
Metabotropic glutamate receptors control gating of spike transmission in the hippocampus
Pharmacol Biochem Behav 2002; 73(2):307-316
Radial Maze